Protein Alignment Ugt37B1 and Ugt1a2

DIOPT Version :9

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 567
• Identity: 151/567 - (26%)
• Similarity: 262/567 - (46%)
• Gaps: 86/567 - (15%)

  Fly     3 GISRCLALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTV----VTI-LKPP 62
            |||..|.|  :..:..|.||.:|.|  .:..|..:....:.|.|..|||...|    ||: :|..
Mouse    11 GISGLLLL--LCALPWAEGAKVLVL--PMEGSQWLSMRDVVRELHARGHQTVVLASEVTVHIKGE 71

  Fly    63 SLHKDINHILVPMEEDILQAFNSVVGGMTKTDNSNAYVSMF----RSVRQLSETFSK--MGDVMK 121
            .......:.....:|:..|   .::..:.||..:..:|..|    .|:|...:.:|.  :..:..
Mouse    72 DFFTLKTYAFPYTKEEYQQ---EILSDIEKTFKTQHFVKAFFETTASIRNFFDLYSNSCIALLHN 133

  Fly   122 QPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGY---LLGNPWEVSY 183
            :.|::.|   ..:.||:::......| ...||..|::|.|..|.:....:.|   ...||  .||
Mouse   134 KMLIQQL---NSSFFDVILTDPIFPC-GAVLAKYLQIPAVFILRSLSCGIEYEATQCPNP--SSY 192

  Fly   184 VPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYED-----L 243
            :|.:...:  ...:.|..||.|:|..:   :..:|..|              ::..||.     |
Mouse   193 IPNLLTRL--SDHMDFLQRVQNMLYYL---VLKYICRL--------------SITPYESLASELL 238

  Fly   244 HKNISLIFFASHG---------ISEGPIRPNVPAVIEIGGIQ-VKEQPERLPQNMEQFL-SEAPN 297
            .:.:||:...||.         :.:.| ||.:|.::.||||. |.::|  |.|..|.:: :...:
Mouse   239 QREVSLVEVLSHASVWLFRGDFVLDYP-RPIMPNMVFIGGINCVTKKP--LSQEFEAYVNASGEH 300

  Fly   298 GAILLSLGSNLKEDHLKSSTVQKMFNVLSKLQQKVIWKWDDL--DNIPGESENILYSKWVPQVDV 360
            |.::.||||.:.|  :......::...|.::.|.|:|::...  .|:   ::|.:..||:||.|:
Mouse   301 GIVVFSLGSMVSE--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDL 360

  Fly   361 LAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQ 425
            |.||....||||:|..|:.|...:|.||:.:|:||||..||..|...|.|:..::|.:..|....
Mouse   361 LGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLEN 425

  Fly   426 GIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVH-MSYIAANNL 489
            .::.|::|..|...:...|:|::|||:.|.:..::|||||:|:.||||:: |..| :::...::|
Mouse   426 ALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSL 489

  Fly   490 DVYAVILGTIVALCFIT--------KLLFGLVVGKLR-KNSRKAKVN 527
            ||...:|..::.:.||.        :..||   ||.| |.|.|:|.:
Mouse   490 DVIGFLLAIVLTVVFIVFKCCAYGCRKCFG---GKGRVKKSHKSKTH 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	144/552 (26%)
		egt	13..483	CDD:223071	131/502 (26%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	139/537 (26%)
		Glycosyltransferase_GTB_type	43..>175	CDD:299143	29/138 (21%)
		egt	<261..505	CDD:223071	80/252 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840656
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H86211
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840