Protein Alignment Ugt37B1 and ugt-47

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_505595.2
• Gene: ugt-47 / 187570
• WormBaseID: WBGene00011006
• Length: 536
• Species: Caenorhabditis elegans
• Alignment Length: 561
• Identity: 140/561 - (24%)
• Similarity: 236/561 - (42%)
• Gaps: 80/561 - (14%)

  Fly     8 LALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVV---------------- 56
            |.|.|:..........||....:.|.|||:....:|..||:.|||||::
 Worm     8 LLLAILYFFEYGLAYKILVFSPATSKSHLISNGRIADELAKAGHNVTLLEIDFLGIVDSTKSAKL 72

  Fly    57 ---TILKPPSLHKDINHILVPMEEDILQ---AFNSVVGGMTKTDNSNAYVSMFRSVRQLSETFSK 115
               ||::.|...:...:::....|.:::   .|..:.|.:       ||.:::   ..|.|.|.:
 Worm    73 VKKTIVRVPKKMQGFKNVIQSFSEGVMEDEGLFELLKGNI-------AYQTVY---NDLCEEFLE 127

  Fly   116 MGDVMKQPLVKDLYEHPDNKFDLVMVGYF---MNCYQLALAHKLKVPLVVALSNPPSFLGYL--- 174
             .:||...|       .|..||    .:|   :|......|..|.:.....:|:.| |..::
 Worm   128 -NEVMFNKL-------KDENFD----AFFAEQLNICGFGYAKALGIQRKFLISSCP-FFSHVYDY 179

  Fly   175 LGNPWEVSYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPS 239
            ..:|...:.||  .:|....:|. :..|..|||..:....|.:....|...|:|:.:|||  .|:
 Worm   180 TSHPAPYASVP--FISDMSPEPT-YLERTNNLLRGITINTFFYFSHNRLTSIFRKKFGDD--FPA 239

  Fly   240 YEDLHKNISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQPERLPQNMEQFLSEAPNGAILLSL 304
            ..::.:|:.:||.|:..|.:.. .|.:|.::.:||:.|.:....:....|..:.:...|.|..||
 Worm   240 ITEIVRNVDIIFLATDEIIDFS-SPTLPNLVHVGGLGVDDDTTEMGPVFEAEMKKGDKGVIYFSL 303

  Fly   305 GSNLKEDHLKSSTVQKMFNVLSKL-QQKVIWKWDDLD----NIPGESENILYSKWVPQVDVLAHP 364
            |:......:....::....::.|. ....:.:.|..|    :...|..|:..|.|:||..:|.||
 Worm   304 GTIANTSTIDKKVMESFLEIVKKFPDYHFLIRADKNDKNTKDKATEISNVFVSDWLPQPAILHHP 368

  Fly   365 NITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGI---KQSILTLEEDSFLQG 426
            .:..||||||..||.||...|.|::.:|...||..|:..:...|:||   |:..|| |.::..:.
 Worm   369 RLRTFITHAGYNGLMEAALAGVPLITIPFMFDQNLNSRAIEKKGWGIRRDKKQFLT-EPNAIEEA 432

  Fly   427 IREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVHMSYIAANNLDV 491
            |||:|.||.|.........|.|::|:..|:..|...|:||:..|...:.:....:|.|...|||:
 Worm   433 IREMLTNPSYTKQAHRVRDLMRNKPMGARDRFIKTTEWVIQNGGVHELLTEGRDLSIIKYYNLDI 497

  Fly   492 YAVILGTIVALCFIT----KLL--------FGLVVGKLRKN 520
              ::....||..||.    ||.        ||.:..|.:|:
 Worm   498 --IVPCFFVAFYFIIFPFFKLFGGFYYYSCFGHIESKYKKD 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	118/474 (25%)
ugt-47	NP_505595.2	GT1_Gtf-like	22..465	CDD:340817	117/472 (25%)