DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37B1 and ugt-36

DIOPT Version :9

Sequence 1:	NP_525008.2	Gene:	Ugt37B1 / 53584	FlyBaseID:	FBgn0026755	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_504820.2	Gene:	ugt-36 / 184266	WormBaseID:	WBGene00017315	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	522	Identity:	131/522 - (25%)
Similarity:	229/522 - (43%)	Gaps:	58/522 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SHLVIQMSMARILAERGHNVTVVTILKPPSL---------HKDINHILVPMEEDILQAFNSVVGG 89
            ||......:|..|...|||||..|    |::         .|.|.|:|.....|.|....|:
Worm    35 SHTTFFAKIADTLTYAGHNVTFFT----PTIVRKFSKIQYVKSITHVLQLDPSDRLVKLGSM--- 92

  Fly    90 MTKTDNSNAYV--SMFRSVRQLSETFSKMGDVMKQPLVKDLYEHPDNK---FDLVMVGYFMNCYQ 149
            ..:.|.|..:.  |....:..:.:||:.|.......:.::|:...|.|   ||:::..:|:....
Worm    93 FEEKDVSKFWYRDSSLSEMLPMIDTFNNMFVEQAAVISRNLHVLDDLKEMNFDVMIFEHFVEPAY 157

  Fly   150 LALAHKLKVPLVVALSNPPSFLGY------LLGNPWEVSYVPGMSVSIKGGKPLGFGHRVLNLLG 208
            |.|.: |::...:    |.:.|.:      .:|.|..:|.|| :..|....: :....|::|.:.
Worm   158 LVLDY-LEIQKFI----PATSLAFDYNMVKSIGEPLMLSTVP-LPTSEYSDR-MSLPQRLINAIN 215

  Fly   209 SMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNISLIFFASHGISEGPIRPNVPAVIEIG 273
            .:   :|..:|.....|.||..|....|    :.:....|.:|..|:...:.| |..:...:::|
Worm   216 PL---IFDNLIPKNKYRSYRPPYAPINT----KSIEPFCSAVFTNSNPYIDYP-RATLEKNVQVG 272

  Fly   274 GIQV---KEQPERLPQNMEQFLSEAPNGAILLSLGSNLKEDHLKSSTVQKMFNVLSKLQQ-KVIW 334
            ||.|   |.:.:::....:..|:..|. .:|:|.||.:....:..:....:..||.|... ..||
Worm   273 GISVDIDKLKSQKVSNEWDAVLNLRPK-TVLVSFGSIMLSKDMPINNKITIATVLGKFPDVTFIW 336

  Fly   335 KWDDLD-NIPGESENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQP 398
            |::..| :....:|||.:|.||||..:||.|.::.|.||||.|.:.|..|.|||.:..|:|.||.
Worm   337 KYETNDTSFANGTENIHFSNWVPQTALLADPRLSAFFTHAGLGSVNEVSYLGKPTIMCPIFADQM 401

  Fly   399 SNADVMVMHGFGIKQSILTLEE-DSFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWV 462
            .||.::..|...|:.|...|.. |...:.:.::|.:..|.||.:..:....::|:.|:|.|:...
Worm   402 RNAKMLARHNGSIEISKYDLSNGDKIEEALSKILFDESYKTAAEKLAHQLANQPVKPKELLVRHA 466

  Fly   463 EYVIRYHGAPHIQSPVVHMSYIAANNLDVYAVILGTIVALCFI---------TKLLFGLVVGKLR 518
            |:..::...|.:......||:|....:|:.|:||.|::...|:         :||.|.|.:.|.:
Worm   467 EFAAQFGHLPSLDPHSRQMSFIQYFLIDLTAIILSTVILFLFVLFKLGKLMYSKLPFNLSLVKQK 531

  Fly   519 KN 520
            .|
Worm   532 TN 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	131/522 (25%)
Ugt37B1	NP_525008.2	egt	13..483	CDD:223071	117/474 (25%)
ugt-36	NP_504820.2	Glycosyltransferase_GTB_type	6..507	CDD:299143	124/494 (25%)
ugt-36	NP_504820.2	YjiC	25..455	CDD:224732	110/442 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910