Protein Alignment Ugt37B1 and ugt-4

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001041203.1
• Gene: ugt-4 / 179754
• WormBaseID: WBGene00013905
• Length: 535
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 140/554 - (25%)
• Similarity: 232/554 - (41%)
• Gaps: 93/554 - (16%)

  Fly     4 ISRCL-ALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVT--ILKPPSLH 65
            :||.| .|...||::.......|.:......||:.....:|..||:.||.||...  :::....|
 Worm     1 MSRVLCVLLFSVLVSHVESYKFLVISPVYGYSHMKFMAIIANQLADEGHQVTYFQPFVIEAYLDH 65

  Fly    66 KDINHILVPMEEDILQAFNSVVGGM---TKTDNSNA-YVSMFRSVRQLSETFSKMGDVMKQPLVK 126
            |.:|:.|:    |::..::...|..   ...|..:| |.|.::|.  ||..|.     |.|.||
 Worm    66 KLLNNSLI----DVINYWHDEEGRRHIPPSNDLHDAWYSSKYQSA--LSAVFD-----MPQFLV- 118

  Fly   127 DLYEH---------------PDNKFDLVMVGYFMNCYQLALAHKLKVPLVV---------ALSNP 167
            ..:||               .|..||:|:...|..| .|.||..::...:|         |:::|
 Worm   119 SAWEHMCRKIFQDSELHKILKDKDFDVVIAETFDFC-GLYLADYIQSKSIVSVFTGSRLIAITDP 182

  Fly   168 PSFLGYLLGNPWEVSYVPGMSVSIKGGKPLGFGHRVLNL-----LGSMAQRLFMF----IIELRN 223
                   ||.|..:.|:|..| |...|.......|:.:|     .||....:|.:    |..|.:
 Worm   183 -------LGEPSSLHYIPAPS-SDNFGSSASIFDRINDLYHKYVFGSGYSIIFDWQYNQIARLTH 239

  Fly   224 ARI--YREIYGDDPTLPSYEDLHKNISLIFFASHGISEGPIRPNVPAVIEIGGIQV-KEQPERLP 285
            .::  :::|..|    .:|...:.|..|.|.|          |.:..||.|||..: |....::|
 Worm   240 GKVRHWKKILKD----VTYHFANSNPYLDFAA----------PTISKVIPIGGYDMDKSIQTKIP 290

  Fly   286 QNMEQFLSEAPNGAILLSLGSNLKEDHLKSSTVQKMFNVLSKLQQKV--IWKWDDLDNIPGES-- 346
            ...:..|:|. :..:.:|.||.:|...:..|..:.|..:.:...|.:  :||::|..:|..::
 Worm   291 DEFDSILNER-SLTVYVSFGSMVKAKFMPESYKEAMLRMFTANTQNITFLWKYEDPTDIFFKNRL 354

  Fly   347 -ENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFG 410
             :|::...|.||..:||...:.|||||.|.|...|..|..||.:.:|:..:||.|..::..||..
 Worm   355 PKNVILKDWFPQRALLADKRVKLFITHGGLGSTMELAYAAKPAIVIPLIAEQPDNGKMLARHGSA 419

  Fly   411 ---IKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAP 472
               .|..|...|:.:.|  ::::|.:..|..|....:.:..::|:.|||.:|...|....:...|
 Worm   420 EIYSKHDIPHWEKLNRL--LQKMLQHSSYQKAADRLARVLSNQPIKPRELMIKHSEMAAMFGKMP 482

  Fly   473 HIQSPVVHMSYIAANNLDVYAVIL----GTIVAL 502
            .:...|..||.|...|||:..:.|    ||.|.|
 Worm   483 ELTPSVQDMSIIEFYNLDIIFLFLIISIGTSVLL 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	120/488 (25%)
ugt-4	NP_001041203.1	GT1_Gtf-like	20..459	CDD:340817	115/476 (24%)