Protein Alignment Ugt37B1 and ugt-25

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_491438.1
• Gene: ugt-25 / 172087
• WormBaseID: WBGene00015692
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 147/554 - (26%)
• Similarity: 242/554 - (43%)
• Gaps: 73/554 - (13%)

  Fly    12 IVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTV--------------------V 56
            |::.:...:..|||....|...||......:|..|.|.|||||.                    |
 Worm     8 ILLSVINVNAFNILVYSPSFGGSHTNFMARLADTLTEAGHNVTFVVPVADEARKGQLGVKKTKDV 72

  Fly    57 TILKPPSLHKDINHILVPMEEDILQAFNSVVGGMTKTDNSNA--YVSMFRSVRQLSETFSKMGDV 119
            .|::...|.|.   .:.|:::|:.|.:.      |..|:|||  ..|:|.....||     ..:.
 Worm    73 VIVEQDELMKS---EIKPLDDDMAQYWE------TDMDSSNADSIFSVFSDAMLLS-----CNNF 123

  Fly   120 MKQPLVKDLYEHPDNKFDLVMVGYF--MNCYQLALAHKLKVPLVVALSNPPSFLGYL--LGNPWE 180
            |:..  |...|.....||   ||.:  ::...|...|.:.:..::..|:...:.|.:  :|.|.:
 Worm   124 MRNK--KVFNELKSRNFD---VGIYEPLSVCGLGYMHAIGINKLIMSSSCALYDGTVAAIGEPID 183

  Fly   181 VSYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHK 245
            .||||| |:| |.|:.:....::.|...|||.....:....:...||::..|:|  :|.:.||..
 Worm   184 FSYVPG-SMS-KSGEKMSLFEKLENYRLSMASSRMQYGQWDKETEIYKKHLGND--IPHWRDLMP 244

  Fly   246 NISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQ---PERLPQNMEQFLSEAPNGAILLSLGSN 307
            :.|:.|..|....:.| |......:.||||.|..:   .::|.......|.|.|:. :|:|.||.
 Worm   245 SSSVAFTNSIPYVDFP-RSITQKTVPIGGISVDMEMIKSQKLSIEWSTVLDERPHN-MLISFGSM 307

  Fly   308 LKEDHLKSSTVQKMFNVL-SKLQQKVIWKWDDLDNIPGES--ENILYSKWVPQVDVLAHPNITLF 369
            ::...:.......:...: |:.....|||::: ||:....  :||.:||||||..:|....:|.|
 Worm   308 VRSMDMPLKWRNGLLEAIKSEPNVTFIWKYEN-DNLEWAKGIQNIYFSKWVPQTALLNDARLTAF 371

  Fly   370 ITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEE------DSFLQGIR 428
            :||.|.|...|..:.|||.|.:|||.||..||:::..||     .:|.:.:      .:....||
 Worm   372 MTHGGLGSTNELAFLGKPALMVPVFADQDRNANMLARHG-----GVLVVHKKELGNFKTIKSSIR 431

  Fly   429 EVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVHMSYIAANNLDVYA 493
            .:|...||....:..|.|..::||.|:|.::.:.|:|.::...|.:.|....:.:|..|.:|:||
 Worm   432 SILHEEKYQKNARKLSELLNNQPLKPKEQVVKYTEFVAKFGPFPQMDSYGRQLGFIQRNLIDIYA 496

  Fly   494 VI----LGTIVALCFITKLLFGLVVGKLRKNSRK 523
            .|    |..|..:.|:.|.:......||.|..:|
 Worm   497 AISLSYLFVISLIYFVFKFVISKTPLKLVKLVKK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	128/476 (27%)
ugt-25	NP_491438.1	GT1_Gtf-like	19..464	CDD:340817	128/475 (27%)