Protein Alignment Ugt37B1 and Ugt1a7c

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_569091.2
• Gene: Ugt1a7c / 154516
• RGDID: 620950
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 550
• Identity: 159/550 - (28%)
• Similarity: 255/550 - (46%)
• Gaps: 50/550 - (9%)

  Fly     4 ISRCLALQIVVLIAGAHGANILGLFTSLSPSH-LVIQMSMARILAERGHNVTVVTILKPPSLHKD 67
            |...|.|.:.:|:|...|.....|...:..|| ..:||.:.::| .:||.|.||.......|.|.
  Rat     6 IPASLPLGLCLLLASGFGHAGKLLVVPMDGSHWFTMQMVVEKLL-PKGHEVVVVVPEVSWQLGKP 69

  Fly    68 IN-----HILVPMEEDILQAFNSVVGGMTKTDNSNAYVSMFRSVRQ--LSETFSKMGDVMKQPLV 125
            :|     :.:...:||:.:.|...:....||......:.:..|..|  ....||....:.|.
  Rat    70 LNFTVKTYSVSHTQEDLNREFKFFIDSQWKTQQEGGVLPLLTSPAQGFFELLFSHCRSLFKD--- 131

  Fly   126 KDLYEH-PDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYLLGN---PWEVSYVP- 185
            |.|.|: ..:.||.|.:..|..| .|.:|....:|.||  .:...|..||...   |...||||
  Rat   132 KKLVEYLKQSSFDAVFLDPFDVC-GLTVAKYFSLPSVV--FSRGIFCHYLEEGSQCPSPPSYVPR 193

  Fly   186 GMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNISLI 250
            |:   :|....:.|..||.|||..|.:..|..........|..|:.....|:   .||...:|:.
  Rat   194 GI---LKLTDTMTFKERVWNLLSYMGEHAFCPSFFKTATDIASEVLQTPVTM---TDLFSPVSVW 252

  Fly   251 FFASHGISEGPIRPNVPAVIEIGGIQVKEQPERLPQNMEQFL-SEAPNGAILLSLGSNLKEDHLK 314
            ...:....|.| ||.:|.||.||||.. .|.:.|.:..|.:: :...:|.::.||||.:.|  :.
  Rat   253 LLRTDFTLELP-RPVMPNVIHIGGINC-HQRKPLSKEFEAYVNASGEHGIVVFSLGSMVSE--IP 313

  Fly   315 SSTVQKMFNVLSKLQQKVIWKWDDL--DNIPGESENILYSKWVPQVDVLAHPNITLFITHAGKGG 377
            .....::...|.::.|.|:|::...  .|:   ::|.:..||:||.|:|.||....||||:|..|
  Rat   314 EKKAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLGHPKARAFITHSGSHG 375

  Fly   378 LTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKS 442
            :.|...:|.||:.:|:||||..||..|...|.|:..::|.:..|.....::.|::|..|...:..
  Rat   376 IYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMR 440

  Fly   443 FSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVH-MSYIAANNLDVYAVILGTIVALCFIT 506
            .|:|::|||:.|.:..::|||||:|:.||||:: |..| :::...::|||...:|..::.:.||.
  Rat   441 LSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIV 504

  Fly   507 --------KLLFGLVVGKLR-KNSRKAKVN 527
                    :..||   ||.| |.|.|:|.:
  Rat   505 YKSCAYGCRKCFG---GKGRVKKSHKSKTH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	126/454 (28%)
Ugt1a7c	NP_569091.2	UDPGT	26..522	CDD:278624	148/519 (29%)