Protein Alignment Ugt37B1 and UGT3A1

DIOPT Version :9

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_689617.3
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 523
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 152/564 - (26%)
• Similarity: 262/564 - (46%)
• Gaps: 86/564 - (15%)

  Fly     4 ISRCLALQIVVLIAG---AHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVTILKPPSLH 65
            :.:.:.|.:..|::|   :..|.||.:.| |..||.::...:::||.|.|||||:        ||
Human     2 VGQRVLLLVAFLLSGVLLSEAAKILTIST-LGGSHYLLLDRVSQILQEHGHNVTM--------LH 57

  Fly    66 KDINHILVPMEEDILQAFNSVVGGMTKTDNS-------NAYVSMFRSVRQLSETFSKMGDVMKQP 123
            :....::..::|:  :....|:...:..|:.       ::|:......|:.||...|:.::....
Human    58 QSGKFLIPDIKEE--EKSYQVIRWFSPEDHQKRIKKHFDSYIETALDGRKESEALVKLMEIFGTQ 120

  Fly   124 LV-----KDLYEHPDNK-FDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYLLGNPWEVS 182
            ..     ||:.:...|: :|||.|..|..| ...:|.||..|.|..|  |.:|.....|.|..:|
Human   121 CSYLLSRKDIMDSLKNENYDLVFVEAFDFC-SFLIAEKLVKPFVAIL--PTTFGSLDFGLPSPLS 182

  Fly   183 YVPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIY----------GDDPTL 237
            |||.....:.  ..:.|..||.|.|        ||....|:....:..:          |..|.|
Human   183 YVPVFPSLLT--DHMDFWGRVKNFL--------MFFSFSRSQWDMQSTFDNTIKEHFPEGSRPVL 237

  Fly   238 PSYEDLHKNISL-IFFASHGISEGPIRPNVPAVIEIGGIQVKEQP-ERLPQNMEQFLSE-APNGA 299
            .     |..:.. ::|.:...:....||.:|..:.|||:.  |:| :.:||:::.|::. ...|.
Human   238 S-----HLLLKAELWFVNSDFAFDFARPLLPNTVYIGGLM--EKPIKPVPQDLDNFIANFGDAGF 295

  Fly   300 ILLSLGSNLKEDHLKSSTVQKMFNVLSKLQQKVIW-----KWDDLDNIPGE---SENILYSKWVP 356
            :|::.||.| ..|.....::||.|..:.|.|.|||     .|      |.:   :.|:....|:|
Human   296 VLVAFGSML-NTHQSQEVLKKMHNAFAHLPQGVIWTCQSSHW------PRDVHLATNVKIVDWLP 353

  Fly   357 QVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEED 421
            |.|:||||:|.||:||.|:..:.||..||.||:.|||.|||..|...:|...:|:...:..:..|
Human   354 QSDLLAHPSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTAD 418

  Fly   422 SFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHI-----QSPVVHM 481
            :....:::|:::.:|.:||.:.|.:...:||||.:.|:.|::::::..||.|:     |.| .|.
Human   419 TLTLTMKQVIEDKRYKSAVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQP-WHE 482

  Fly   482 SYIAANNLDVYAVILGTIVALCFITKLLFGLVVGKLRKNSRKAK 525
            .|:    :||:..:||..:...::...|.|:|...|| .:||.|
Human   483 QYL----IDVFVFLLGLTLGTMWLCGKLLGVVARWLR-GARKVK 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	148/552 (27%)
		egt	13..483	CDD:223071	138/511 (27%)
UGT3A1	NP_689617.3	UDPGT	23..523	CDD:330975	149/543 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150081
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840