Protein Alignment Ugt37B1 and Ugt2b37

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_444445.2
• Gene: Ugt2b37 / 112417
• MGIID: 2148239
• Length: 530
• Species: Mus musculus
• Alignment Length: 585
• Identity: 158/585 - (27%)
• Similarity: 260/585 - (44%)
• Gaps: 113/585 - (19%)

  Fly     4 ISRCLALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAE---RGHNVTVVTILKPPSLH 65
            ||..|.|||...........:|     :.|......|::..||.|   |||.|||:.    ||.:
Mouse     6 ISALLLLQISCCFRSVKCGKVL-----VWPMEFSHWMNIKIILDELVQRGHEVTVLR----PSAY 61

  Fly    66 KDINHILVPMEEDILQAFNSVVGGMTKTDNSNAYVSM-----FRSVRQLSETFSKMGDVMKQPLV 125
                ::|.|.:...|: |.:....:||.|..|.::.:     :...|....::|        ||:
Mouse    62 ----YVLDPKKSPGLK-FETFPTSVTKDDLENFFIQLLNVWTYELSRDTCLSYS--------PLM 113

  Fly   126 KDLYEHPDNKFDLVMVGYFMN-CYQLALAHKLKVPLV-----VALSNPPSFLGYLLGNPWEV--- 181
            :::::.        :.||::: |..:....:|...|.     |.||:|.:|.|.|:.....:
Mouse   114 QNMFDE--------LSGYYLSLCKDVVSNRQLMTKLQESKFDVLLSDPVAFGGELIAELLHIPFL 170

  Fly   182 ----------------------SYVPGMSVSIKG-GKPLGFGHRVLNLLGSMAQRLFMFIIELRN 223
                                  ||||   |.:.| |..:.|..||.|::   ....|.|..::.|
Mouse   171 YSLRFTAGYRIEKSSGRFLLPPSYVP---VILSGLGGQMTFIERVKNMI---CMLYFDFWFQMPN 229

  Fly   224 AR----IYREIYGDDPTLPSYEDLHKNISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQPER- 283
            .:    .|.|..|...||   .:......:....|:...|.| .|.:|.|..:||:..|  |.:
Mouse   230 DKKWDSFYTEYLGRPTTL---AETMGQAEMWLIRSNWDLEFP-HPTLPNVDYVGGLHCK--PAKP 288

  Fly   284 LPQNMEQFL-SEAPNGAILLSLG---SNLKEDHLKSSTVQKMFNVLSKLQQKVIWKWDDLDNIPG 344
            ||::||::: |...:|.::.|||   ||:.|:     .|..:...|:::.|||:||:|  ...|.
Mouse   289 LPKDMEEYVQSSGDHGVVVFSLGSMVSNITEE-----KVNAIAWALAQIPQKVLWKFD--GKTPA 346

  Fly   345 E-SENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHG 408
            . ..|....||:||.|:|.||....||||.|...:.||.|||.||:.:|:||:|..|...||..|
Mouse   347 TLGHNTRVYKWLPQNDLLGHPKTKAFITHGGANSVYEAIYHGIPMIGIPLFGEQHDNIAHMVAKG 411

  Fly   409 FGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPH 473
            ..:..:|.|:.....|..:.||::||.|.......||::.|:|:.|.:..::|||:|:|:..|.|
Mouse   412 AAVTLNIRTMSRSDVLNALEEVIENPFYKKNAMWLSTIHHDQPMKPLDRAVFWVEFVMRHKNAKH 476

  Fly   474 IQSPVVH-MSYIAANNLDVYAVILGTIVALCFITK--LLFGLVVGKLRKNSRKAKVNQKHKLKKK 535
            :: |:.| :::...::|||...:|..:.|...:|.  |||          ..:..|.:|.|:|.:
Mouse   477 LR-PLGHNLTWYQYHSLDVIGFLLACVAATVVLTVKCLLF----------IYRFFVTKKKKMKNE 530

  Fly   536  535
            Mouse   531  530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	130/488 (27%)
Ugt2b37	NP_444445.2	UDPGT	24..527	CDD:278624	150/562 (27%)