Protein Alignment Ugt37B1 and UGT2B11

DIOPT Version :9

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001064.1
• Gene: UGT2B11 / 10720
• HGNCID: 12545
• Length: 529
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 144/529 - (27%)
• Similarity: 239/529 - (45%)
• Gaps: 72/529 - (13%)

  Fly    34 SHLVIQMSMARILAERGHNVTVVTILKPPSLHKDINHILVPMEEDILQAFNSVVGGMTKTDNSN- 97
            ||.:...::.:.|.:|||.|||        |....:.:..|.:...|: |......:|||:..|
Human    34 SHWMNMKTILKELVQRGHEVTV--------LASSASILFDPNDASTLK-FEVYPTSLTKTEFENI 89

  Fly    98 --AYVSMFRSVR---------QLSETFSKMGDVMKQPLVKDLYEH-------PDNKFDLVMVGYF 144
              ..|..:..:|         |..|...::.|:.:. ..||:..:       .:::||:|.....
Human    90 IMQQVKRWSDIRKDSFWLYFSQEQEILWELYDIFRN-FCKDVVSNKKVMKKLQESRFDIVFADAV 153

  Fly   145 MNCYQLALAHKLKVPLVVALSNPPSFL-----GYLLGNPWEVSYVPGMSVSIKGGKPLGFGHRVL 204
            ..|.:| ||..|.:..|.:|...|.:.     |.|:..|   ||:|  .|..|....:.|..||.
Human   154 FPCGEL-LAALLNIRFVYSLRFTPGYTIERHSGGLIFPP---SYIP--IVMSKLSDQMTFMERVK 212

  Fly   205 NLLGSMAQRLFMFIIELRNAR----IYREIYGDDPTLPSYEDLHK-NISLI-----FFASHGISE 259
            |::..:   .|.|..::.:.:    .|.|:.|...||  :|.:.| :|.|:     |...|
Human   213 NMIYVL---YFDFWFQMSDMKKWDQFYSEVLGRPTTL--FETMGKADIWLMRNSWSFQFPH---- 268

  Fly   260 GPIRPNVPAVIEIGGIQVKEQPER-LPQNMEQFL-SEAPNGAILLSLGSNLKEDHLKSSTVQKMF 322
             |..|||..|   ||...|  |.: ||:.||:|: |...||.::.||||.:  .::.:.....:.
Human   269 -PFLPNVDFV---GGFHCK--PAKPLPKEMEEFVQSSGENGVVVFSLGSVI--SNMTAERANVIA 325

  Fly   323 NVLSKLQQKVIWKWDDLDNIPGE-SENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGK 386
            ..|:|:.|||:|::|  .|.|.. ..|....||:||.|:|.||....||||.|..|:.||.|||.
Human   326 TALAKIPQKVLWRFD--GNKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGI 388

  Fly   387 PMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRP 451
            ||:.:|:|.|||.|...|...|..::....|:.....|..::.|:::|.|...:...|.:..|:|
Human   389 PMVGIPLFFDQPDNIAHMKAKGAAVRLDFNTMSSTDLLNALKTVINDPLYKENIMKLSRIQHDQP 453

  Fly   452 LSPRETLIYWVEYVIRYHGAPHIQSPVVHMSYIAANNLDVYAVILGTIVALCFITKLLFGLVVGK 516
            :.|.:..::|:|:|:.:.||.|::.....:::...::|||...:|..:..:.||..........|
Human   454 VKPLDRAVFWIEFVMPHKGAKHLRVAAHDLTWFQYHSLDVIGFLLACVATVIFIITKFCLFCFWK 518

  Fly   517 LRKNSRKAK 525
            ..:..:|.|
Human   519 FARKGKKGK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	142/525 (27%)
		egt	13..483	CDD:223071	135/485 (28%)
UGT2B11	NP_001064.1	UDPGT	24..525	CDD:278624	142/525 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150536
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840