Protein Alignment Ugt37B1 and Ugt3a2

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_997099.2
• Gene: Ugt3a2 / 105887
• MGIID: 2146055
• Length: 523
• Species: Mus musculus
• Alignment Length: 551
• Identity: 157/551 - (28%)
• Similarity: 265/551 - (48%)
• Gaps: 79/551 - (14%)

  Fly    10 LQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNV--------TVVTILKPPSLHK 66
            |::::|.|    |.||.:.| ||.||.::...:::||...||:|        .:....|..|.::
Mouse    15 LEVLLLEA----AKILTIST-LSASHYILMNRVSQILQGGGHDVIKLLYEGGDIPDFRKENSSYQ 74

  Fly    67 DINHILVPMEEDILQAFNSVVGGMTKTDNSNAY-VSMFRSVRQLSETFSKMGDVMKQPLV-KDLY 129
            .||..|   .||..:.|.:   ...:..:..|| .|.:.::.::.:.|:   |:....|. ||:.
Mouse    75 VINWRL---PEDQQKTFEN---RWHRLIDEYAYGRSKYHTLLKIHQYFA---DLCSHLLSRKDIM 130

  Fly   130 E--HPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYLLGNPWEVSYVP--GMSVS 190
            |  ..:| ||||::. .|:.....:..||....|..|....|::.:.|.|. .:||.|  |..::
Mouse   131 ELLQKEN-FDLVLLD-SMDLCSFLIVEKLGKRFVSFLPFQFSYMDFGLPNA-PLSYAPVYGSGLT 192

  Fly   191 IKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGD-------DPTLPSYEDLHKNIS 248
                ..:.|..||.|:|        ||....:..|.....||:       :.:.|...||.....
Mouse   193 ----DQMDFWGRVKNIL--------MFFHFTKKRRDIFSQYGNTVQEHFAEGSQPVLSDLLLKAE 245

  Fly   249 LIFFASHGISEGPIRPNVPAVIEIGGIQVKE-QPERLPQNMEQFLSE-APNGAILLSLGSNLKED 311
            | :|.:...:....||..|..:.:||:..|. ||  :||::|.|:|: ..:|.:|::|||.:...
Mouse   246 L-WFVNSDFALDFARPLFPNTVYVGGLLDKPVQP--IPQDLEDFISQFGDSGFVLVALGSVVSMI 307

  Fly   312 HLKSSTVQKMFNVLSKLQQKVIW-----KW-DDLDNIPGESENILYSKWVPQVDVLAHPNITLFI 370
            ..| ..:::|.:..:.|.|.|:|     .| .|:...|    |:....|:||:|:||||:|.||:
Mouse   308 QSK-EIIKEMNSAFAHLPQGVLWTCKSSHWPKDVSLAP----NVKIMDWLPQIDLLAHPSIRLFV 367

  Fly   371 THAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPK 435
            ||.|...:.||.:||.||:.:|.|||||.|...:.....|:...:.||:.:|||..::||:::.:
Mouse   368 THGGMNSVMEAVHHGVPMVGIPFFGDQPENMVRVEAKNLGVSIQLQTLKAESFLLTMKEVIEDQR 432

  Fly   436 YATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHI-----QSPVVHMSYIAANNLDVYAVI 495
            |.||..:...:.:..||:|.:.|:.|::::::..||.|:     |.| .|..|:    |||:..:
Mouse   433 YKTAAMASKVIRQSHPLTPAQRLVGWIDHILQTGGAAHLKPYAFQQP-WHEQYM----LDVFLFL 492

  Fly   496 LG-TIVALCFITKLLFGLVVGKLRKNSRKAK 525
            || |:..|....|:|  :.|.:....|||.|
Mouse   493 LGLTLGTLWLSVKVL--VAVTRYLSISRKVK 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	132/467 (28%)
Ugt3a2	NP_997099.2	Glycosyltransferase_GTB-type	24..488	CDD:471961	140/501 (28%)