Protein Alignment Ugt37C1 and UGT2A3

DIOPT Version :9

• Sequence 1: NP_525007.1
• Gene: Ugt37C1 / 53583
• FlyBaseID: FBgn0026754
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_011530549.1
• Gene: UGT2A3 / 79799
• HGNCID: 28528
• Length: 533
• Species: Homo sapiens
• Alignment Length: 514
• Identity: 140/514 - (27%)
• Similarity: 237/514 - (46%)
• Gaps: 98/514 - (19%)

  Fly    11 GHNVTVVSMMQPKVM--HKDIHLIVVPVTKEQERTLENQMASMAGSKNNIITTMYLLLNGLDVMV 73
            ||.|||::..:|.::  .|...|....|...|:||.||::            .:.|.||.|..:.
Human    50 GHEVTVLTHSKPSLIDYRKPSALKFEVVHMPQDRTEENEI------------FVDLALNVLPGLS 102

  Fly    74 TSQADLLKDPRFQRVFETKFDLMILGSFFNDFQLGVAGKLKV---------------------PV 117
            |.|: ::|                    .|||.:.:.|.||:                     .:
Human   103 TWQS-VIK--------------------LNDFFVEIRGTLKMMCESFIYNQTLMKKLQETNYDVM 146

  Fly   118 IVDWMIPSNTMIDEFVA---------------------NPSEVSYVPNESTFATTPMSFFKRAEN 161
            ::|.:||...::.|.:|                     .|:.:||||...|..|..|:|.:|.:|
Human   147 LIDPVIPCGDLMAELLAVPFVLTLRISVGGNMERSCGKLPAPLSYVPVPMTGLTDRMTFLERVKN 211

  Fly   162 LVKHVILKYLTIRFNYKFNRIYNEIFTDKDM---PTLSEMKKNISMVFVGSHLISDGPIRPLVPA 223
            .:..|:..:....::|.|    .|.|..|.:   .||.|......:..:.::...:.| :|..|.
Human   212 SMLSVLFHFWIQDYDYHF----WEEFYSKALGRPTTLCETVGKAEIWLIRTYWDFEFP-QPYQPN 271

  Fly   224 IIEVGGIQVKEQPDPLP------QDIEQFMENSSQ-GAIFLSFGSNIKSYMVKPEIVGIMFKVLS 281
            ...|||:..| ....||      |::|.|:::|.: |.:..|.||..::  |..|...|:...|:
Human   272 FEFVGGLHCK-PAKALPKINFYLQEMENFVQSSGEDGIVVFSLGSLFQN--VTEEKANIIASALA 333

  Fly   282 GLKQNVIWKWEDLENTPGNASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVAL 346
            .:.|.|:|:::..:.:...|:...| ||:||:|:|.||.||.|:||.|...|.|:.|||||||.:
Human   334 QIPQKVLWRYKGKKPSTLGANTRLY-DWIPQNDLLGHPKTKAFITHGGMNGIYEAIYHGVPMVGV 397

  Fly   347 PIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQ 411
            |||||...|.|.|...|..|.::.:|:|.:....|:..|:.:..|.:...:.|.::.|:|:.|..
Human   398 PIFGDQLDNIAHMKAKGAAVEINFKTMTSEDLLRALRTVITDSSYKENAMRLSRIHHDQPVKPLD 462

  Fly   412 SVLFWVDYVLRHHGAPNLQSPAVHMGFVELHNLDIYALVLAILIFLVFLTRLTVKFLFS 470
            ..:||:::|:||.||.:|:|.|..:.:.:.:::|:...:||.:...:||  .|..||||
Human   463 RAVFWIEFVMRHKGAKHLRSAAHDLTWFQHYSIDVIGFLLACVATAIFL--FTKCFLFS 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	140/514 (27%)
		egt	6..433	CDD:223071	129/475 (27%)
UGT2A3	XP_011530549.1	UDPGT	24..528	CDD:278624	140/514 (27%)
		egt	<267..498	CDD:223071	78/234 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150241
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740