DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C1 and ugt5c2

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001038851.1	Gene:	ugt5c2 / 751669	ZFINID:	ZDB-GENE-060825-206	Length:	552	Species:	Danio rerio

Alignment Length:	494	Identity:	144/494 - (29%)
Similarity:	243/494 - (49%)	Gaps:	46/494 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KALAEAGHNVTVVS-----MMQPKVMHKDIHLIVVPVTK--EQERTLE--NQMASMAGSKNNIIT 60
            |||...||.|.|:.     .::....:.|  .|.:|.||  ::|...:  .:|......|.:.::
Zfish    69 KALHGQGHTVDVIRNANSWFIKENSTYYD--TITIPNTKGWDEEFAADFVYKMIKYEKEKGSWLS 131

  Fly    61 TMYLLLNGLDV----------MVTSQADLLKDPRFQRVFETKFDLMILGSFFNDFQLGV--AGKL 113
            .:.|.||..|.          ::|:..|  .:...:.:.|.::|||:....:.   .|:  |.||
Zfish   132 IVRLYLNVFDAVKKTHEMVCQLITNILD--SEEILKMLNEKQYDLMLTDPVWG---TGIILAHKL 191

  Fly   114 KVPVI--VDWMIPSNTMIDEFVANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFN 176
            |:|::  |.|   :.|....|...||.:||:|...:..|..||||:|.:|...:::|......||
Zfish   192 KLPMVYNVRW---TTTGEGHFDIAPSPMSYIPITGSGNTDRMSFFQRLKNYFFYLLLDLQLSHFN 253

  Fly   177 YK-FNRIYNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLP 240
            .| :..|.::.||.:  ....|:.:...:..:....:.:.| ||.:|.||.:||.|. ....|||
Zfish   254 VKQYQAICDKYFTSR--VNFHELLQGADLWLMRVDFVFEFP-RPTMPNIIYIGGFQC-PPAKPLP 314

  Fly   241 QDIEQFMENS-SQGAIFLSFGSNIKSYMVKPE-IVGIMFKVLSGLKQNVIWKWEDLENTPGNAS- 302
            .|:|.||::| ..|.|.:|.||.|.:.   || :...:....:.|.|.|||::..  ..|...|
Zfish   315 HDLEDFMQSSGDHGVIVMSLGSLIGNL---PENVTAEIAAAFARLPQKVIWRYTG--KKPSTLSN 374

  Fly   303 NIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVS 367
            |....||:||.|:|.||.||:|::|.|...:.|:.|||||::.:|.|.|...|...:...|....
Zfish   375 NTLMVDWMPQKDLLGHPKTKVFISHGGTNGVLEALYHGVPVIGIPFFFDQYDNLIRLQARGGAKL 439

  Fly   368 LDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSP 432
            |.:..:.|:|...||.||:....|...:.|.|.|::|:|:.|..|.:||:::|:||.||.:|::.
Zfish   440 LSIADLGENTLHAAIQEVINEPSYRLNMHKLSHLHKDKPVKPLDSAIFWIEFVMRHKGAAHLRTE 504

  Fly   433 AVHMGFVELHNLDIYALVLAILIFLVFLTRLTVKFLFSK 471
            :..|.:...|::|:...:.|:::.|.:...:||::|..|
Zfish   505 SYKMPWYSYHSVDVVVTLFAVVLILTYCIFVTVRYLCVK 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	144/494 (29%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	134/453 (30%)
ugt5c2	NP_001038851.1	UDPGT	49..551	CDD:278624	144/494 (29%)
ugt5c2	NP_001038851.1	egt	<288..528	CDD:223071	84/246 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585121
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.740