Protein Alignment Ugt37C1 and UGT8

DIOPT Version :9

• Sequence 1: NP_525007.1
• Gene: Ugt37C1 / 53583
• FlyBaseID: FBgn0026754
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001121646.2
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 136/500 - (27%)
• Similarity: 245/500 - (49%)
• Gaps: 69/500 - (13%)

  Fly     4 AKALAEAGHNVTVVSMMQPKVMHKDIHLIV-----VPVTKEQERTLENQMASMAGSKNNIITTMY 63
            |.||.|.||: ||..:.:.:.:....|..:     :..:...:..|:::|.::...:...|....
Human    42 ASALHERGHH-TVFLLSEGRDIAPSNHYSLQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAIELFD 105

  Fly    64 LL---LNGLDVMVTSQADLLKDPRFQRVFETKFDLM--------------ILGSFFNDFQLGVAG 111
            :|   ....|:||.:.|      ..|.:.:.||||:              :||..:..|..|:
Human   106 ILDHYTKNCDLMVGNHA------LIQGLKKEKFDLLLVDPNDMCGFVIAHLLGVKYAVFSTGL-- 162

  Fly   112 KLKVPVIVDWMIPSNTMIDEFVANPSEVSYVPNESTFATTPMSFFKRAEN----LVKHVILKYLT 172
                     | .|:.      |..|:.::|||..::..|..|:..:|.:|    |:..:.:.:|.
Human   163 ---------W-YPAE------VGAPAPLAYVPEFNSLLTDRMNLLQRMKNTGVYLISRLGVSFLV 211

  Fly   173 IRFNYKFNRI---YNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKE 234
            :.   |:.||   || :..:|.|   .::....|:..:.:.:..:.| ||.:|.::.||||..|
Human   212 LP---KYERIMQKYN-LLPEKSM---YDLVHGSSLWMLCTDVALEFP-RPTLPNVVYVGGILTK- 267

  Fly   235 QPDPLPQDIEQFMENSSQ-GAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTP 298
            ...|||:|:::::..::: |.:.:|||:.:|  .:..:|...:...|..|.|.|||::...:  |
Human   268 PASPLPEDLQRWVNGANEHGFVLVSFGAGVK--YLSEDIANKLAGALGRLPQKVIWRFSGPK--P 328

  Fly   299 GN-ASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNS 362
            .| .:|....:||||:|:|.|...|.|::|.|..||.|:.|||||:|.:|:||||......:...
Human   329 KNLGNNTKLIEWLPQNDLLGHSKIKAFLSHGGLNSIFETIYHGVPVVGIPLFGDHYDTMTRVQAK 393

  Fly   363 GYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAP 427
            |.|:.|:.:|:||....||:.:|:.|..|.|..:|.|.:::|:|..|....::|:||::||:||.
Human   394 GMGILLEWKTVTEKELYEALVKVINNPSYRQRAQKLSEIHKDQPGHPVNRTIYWIDYIIRHNGAH 458

  Fly   428 NLQSPAVHMGFVELHNLDIYALVLAILIFLVFLTRLTVKFLFSKL 472
            :|::....:.|.:...|||..::|.....|.||.....||::.|:
Human   459 HLRAAVHQISFCQYFLLDIAFVLLLGAALLYFLLSWVTKFIYRKI 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	136/499 (27%)
		egt	6..433	CDD:223071	124/457 (27%)
UGT8	NP_001121646.2	Glycosyltransferase_GTB-type	21..502	CDD:415824	135/497 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150682
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740