Protein Alignment Ugt37C1 and UGT2B15

DIOPT Version :9

• Sequence 1: NP_525007.1
• Gene: Ugt37C1 / 53583
• FlyBaseID: FBgn0026754
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001067.2
• Gene: UGT2B15 / 7366
• HGNCID: 12546
• Length: 530
• Species: Homo sapiens
• Alignment Length: 509
• Identity: 147/509 - (28%)
• Similarity: 254/509 - (49%)
• Gaps: 55/509 - (10%)

  Fly     7 LAEAGHNVTVVSMMQPKVMHKD----IHLIVVPVTKEQERTLENQMASMAG------SKNNIITT 61
            |.:.||.|||::.....:::..    |.|.|.| |...:..||:.:..:..      |||    |
Human    46 LVQRGHEVTVLTSSASTLVNASKSSAIKLEVYP-TSLTKNYLEDSLLKILDRWIYGVSKN----T 105

  Fly    62 MYLLLNGLDVMVTSQAD----LLKD-----PRFQRVFETKFDLMILGSFFNDFQLGVAGKLKVPV 117
            .:...:.|..:.....|    |.||     ....::.|:||| :||....|.....:|....:|.
Human   106 FWSYFSQLQELCWEYYDYSNKLCKDAVLNKKLMMKLQESKFD-VILADALNPCGELLAELFNIPF 169

  Fly   118 IVDWMIPSNTMIDE----FVANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNY- 177
            :...........::    |:..|   ||||...:..:..|.|.:|.:|:: |::  |....|..
Human   170 LYSLRFSVGYTFEKNGGGFLFPP---SYVPVVMSELSDQMIFMERIKNMI-HML--YFDFWFQIY 228

  Fly   178 ---KFNRIYNEIFTDKDMP-TLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDP 238
               |:::.|:|:.   ..| ||.|......|..:.::...:.| ||.:|.:..|||:..| ...|
Human   229 DLKKWDQFYSEVL---GRPTTLFETMGKAEMWLIRTYWDFEFP-RPFLPNVDFVGGLHCK-PAKP 288

  Fly   239 LPQDIEQFMENSSQ-GAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLE-NTPGNA 301
            ||:::|:|:::|.: |.:..|.||.|.:  :..|...::...|:.:.|.|:|:::..: ||.|:.
Human   289 LPKEMEEFVQSSGENGIVVFSLGSMISN--MSEESANMIASALAQIPQKVLWRFDGKKPNTLGSN 351

  Fly   302 SNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGV 366
            :.: || ||||:|:|.||.||.|:||.|...|.|:.|||:|||.:|:|.|...|.|.|...|..:
Human   352 TRL-YK-WLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAAL 414

  Fly   367 SLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQS 431
            |:|::|::......|:..|:.:..|.:.|.|.|.::.|:|:.|....:||:::|:||.||.:|:.
Human   415 SVDIRTMSSRDLLNALKSVINDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHKGAKHLRV 479

  Fly   432 PAVHMGFVELHNLDIYALVLAILIFLVFLTRLTVKFLFSKLLGKAKVPARKKKQ 485
            .|.::.:::.|:||:.|.:||.:..::|:......|.|.||..|.|    |||:
Human   480 AAHNLTWIQYHSLDVIAFLLACVATVIFIITKFCLFCFRKLAKKGK----KKKR 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	143/499 (29%)
		egt	6..433	CDD:223071	130/455 (29%)
UGT2B15	NP_001067.2	egt	8..508	CDD:223071	137/482 (28%)
		UDPGT	24..518	CDD:278624	139/492 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150292
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740