Protein Alignment Ugt37C1 and UGT2B4

DIOPT Version :9

• Sequence 1: NP_525007.1
• Gene: Ugt37C1 / 53583
• FlyBaseID: FBgn0026754
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_066962.2
• Gene: UGT2B4 / 7363
• HGNCID: 12553
• Length: 528
• Species: Homo sapiens
• Alignment Length: 489
• Identity: 130/489 - (26%)
• Similarity: 239/489 - (48%)
• Gaps: 47/489 - (9%)

  Fly     7 LAEAGHNVTVVSMM--------QPKVMHKDIHLIVVPVTKEQERTLENQMA------------SM 51
            |.:.||.|||::..        .|..:..:::  .|.:||.:...:..|:.            |.
Human    46 LVQRGHEVTVLASSASISFDPNSPSTLKFEVY--PVSLTKTEFEDIIKQLVKRWAELPKDTFWSY 108

  Fly    52 AGSKNNIITTMYLLLNGLDVMVTSQADLLKDPRFQRVFETKFDLMILGSFFNDFQLGVAGKLKVP 116
            ......|:.|...:|......:.|...|:|     ::.|::||:::..:.|...:| :|..||:|
Human   109 FSQVQEIMWTFNDILRKFCKDIVSNKKLMK-----KLQESRFDVVLADAVFPFGEL-LAELLKIP 167

  Fly   117 VIVDWMIPSNTMIDEFVAN---PSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNY- 177
            .:..........|::....   |.  ||||...:..:..|:|.:|.:|::..:..::....|:.
Human   168 FVYSLRFSPGYAIEKHSGGLLFPP--SYVPVVMSELSDQMTFIERVKNMIYVLYFEFWFQIFDMK 230

  Fly   178 KFNRIYNEIFTDKDMP-TLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQ 241
            |:::.|:|:.   ..| ||||......:..:.::.....| .||:|.:..|||:..| ...|||:
Human   231 KWDQFYSEVL---GRPTTLSETMAKADIWLIRNYWDFQFP-HPLLPNVEFVGGLHCK-PAKPLPK 290

  Fly   242 DIEQFMENSSQ-GAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTPGNASNIF 305
            ::|:|:::|.: |.:..|.||.:.:  ...|...::...|:.:.|.|:|:::..:......:...
Human   291 EMEEFVQSSGENGVVVFSLGSMVSN--TSEERANVIASALAKIPQKVLWRFDGNKPDTLGLNTRL 353

  Fly   306 YKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDL 370
            || |:||:|:|.||.|:.|:||.|...|.|:.|||:|||.:|:|.|.|.|.|.|...|..||||.
Human   354 YK-WIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAVSLDF 417

  Fly   371 QTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVH 435
            .|::......|:..|:.:..|.:...|.|.::.|:|:.|....:||:::|:||.||.:|:..|..
Human   418 HTMSSTDLLNALKTVINDPLYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHD 482

  Fly   436 MGFVELHNLDIYALVLAILIFLVFLTRLTVKFLF 469
            :.:.:.|:||:...:||.:..::|   :..|.||
Human   483 LTWFQYHSLDVTGFLLACVATVIF---IITKCLF 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	130/489 (27%)
		egt	6..433	CDD:223071	120/451 (27%)
UGT2B4	NP_066962.2	egt	8..512	CDD:223071	128/486 (26%)
		UDPGT	24..524	CDD:278624	130/489 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150458
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740