DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C1 and ugt5g1

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001107914.1	Gene:	ugt5g1 / 570913	ZFINID:	ZDB-GENE-080305-10	Length:	528	Species:	Danio rerio

Alignment Length:	500	Identity:	160/500 - (32%)
Similarity:	255/500 - (51%)	Gaps:	54/500 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GHNVTVVSMMQPKVMHKDIHL----IVVPVTKEQ----------ERTLENQMAS----MAGSKNN 57
            ||:.|||...:...:|::..|    .|.||..|.          :|:|..|..|    ....:.:
Zfish    50 GHSFTVVRSSKSWYIHENSALYNTITVNPVETEDVGQDYFNMLLDRSLALQKMSPLVRFFEQQKD 114

  Fly    58 IITTMYLLLNGLDVMVTS---QADLLKDPRFQRVFETKFDLMILGSFFNDFQLGVAGKLKVPVI- 118
            |.|.:.:..||:..||::   .|:|:|..|     |.||||::....|....| ||..|::|::
Zfish   115 ITTVLKVFHNGVLRMVSAMLDDAELVKSLR-----EAKFDLLLTDPAFPAGVL-VANFLQLPMVY 173

  Fly   119 -VDWMIPSNTMIDEFVANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYL--TIRFNYKFN 180
             |.|:   |.........||..||||..::.....|||.:|.||     .|:||  .::..|...
Zfish   174 NVRWL---NAGDAHMQTAPSPPSYVPMYNSLLHDQMSFLQRVEN-----FLRYLCSLLQERYVIV 230

  Fly   181 RIYNEIFTDKDMP---TLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQD 242
            .||.|:. ::..|   .|..|:::..:..:....:.|.| ||.:|.||.:||.|.| ....||.|
Zfish   231 PIYRELL-ERHFPPGSDLLSMQQSADIWLMRMDFVFDFP-RPTMPNIIYMGGFQCK-PAQALPVD 292

  Fly   243 IEQFMENSSQ-GAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWE-DLENTPGNASNIF 305
            :|:||::|.: |.:|:|.|:.:.:  :...|...:....:.:.|.|:|::. :..:|.||  |..
Zfish   293 LEEFMQSSGEHGVVFMSLGAMVGA--LPRTITEAIASAFAKIPQKVMWRYHGERPSTLGN--NTL 353

  Fly   306 YKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNA-ALMVNSGYGVSLD 369
            ..:|.||:|:|.||.|:.||:|.|...|.|:.|||||::|||:..|...|. .|.|.:...| |.
Zfish   354 LLEWFPQNDLLGHPKTRAFVSHGGTNGIYEAIYHGVPVLALPLLFDQFDNVMRLQVRNAARV-LQ 417

  Fly   370 LQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAV 434
            :.|:|...|.|.:.:||||..|..::||.|.|:||:|::|..|..||::||:||.||.:|:|.|.
Zfish   418 VATLTSQEFLEGLKDVLENPLYRSSIRKMSELHRDQPISPLDSATFWIEYVMRHKGAAHLRSEAN 482

  Fly   435 HMGFVELHNLDIYALVLAILIFLVFLTRLTVKFL-FSKLLGKAKV 478
            ::.:...|:||:...:|||.:...:.:....:|| ..|.:.|.||
Zfish   483 NLAWYSYHSLDVLVFLLAIAVIAFWTSVYVCRFLCCRKSIKKRKV 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	158/497 (32%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	147/452 (33%)
ugt5g1	NP_001107914.1	UDPGT	24..526	CDD:278624	158/497 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584649
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740