Protein Alignment Ugt37C1 and ugt2a2

DIOPT Version :10

• Sequence 1: NP_525007.2
• Gene: Ugt37C1 / 53583
• FlyBaseID: FBgn0026754
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001018306.2
• Gene: ugt2a2 / 553952
• ZFINID: ZDB-GENE-080721-21
• Length: 534
• Species: Danio rerio
• Alignment Length: 554
• Identity: 153/554 - (27%)
• Similarity: 261/554 - (47%)
• Gaps: 54/554 - (9%)

  Fly     1 MKMLAVFSAIVWLLAVASPSQGANIL---GVYSALSPSHLIIHMSTAKALAEAGHNVTV-VSMMQ 61
            ||.|...|.:| |:.:.|.:...|:|   |.|     ||.....:....|....|.||| |....
Zfish     2 MKCLLKPSPLV-LIFIFSFTHAGNVLVLPGEY-----SHWQNMRNVVDELLNRNHTVTVLVCSAS 60

  Fly    62 PKV----MHKDIHLIV-VPVTKEQERTLENQMA---SMAGSKNNIITTMYL--LLNGLDVMVTSQ 116
            |.:    ..:..:|:. ||::.::......::.   :...|.|.:.|.:.:  ||..:.||..:.
Zfish    61 PTINFTQQERFQYLVFEVPLSAQELDGASEELIHIWTQHPSPNRLQTALQIIELLGRVRVMHRAM 125

  Fly   117 AD--LLKDPRFQRVFETKFDLMILGSFFND--FQLG--VAGKLKVPVIVDWMIPSNTMIDEFVAN 175
            .|  |..|....::...|||::     |||  |...  :|..|.:|:::...|.....::.....
Zfish   126 CDSMLRNDALIAQLSALKFDVL-----FNDPMFMCADLLAEMLGLPLVLSVRISPGFCLERMCGQ 185

  Fly   176 -PSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNYKFNRI----YNEIFTD--KDMP 233
             |:..|:||...|..|..|.|.:|.:|::.:::       |:..|..:    .:..:||  ....
Zfish   186 MPAPPSFVPITQTVLTDRMCFMERVQNMIANIV-------FSVSFYIVAWISLDSYYTDVLGKPT 243

  Fly   234 TLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENS-SQGAIFL 297
            |:.|......:..:.::...:.| ||..|....|||:..| ...||.:::|:|:::| ..|.:..
Zfish   244 TMCETMGKADIWLIRTYWDFEYP-RPFPPNFKFVGGLHCK-PAKPLSKEMEEFVQSSGDHGVVVF 306

  Fly   298 SFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTPGN-ASNIFYKDWLPQDDILAHPNT 361
            |.||.||:  :..|....:...|..:.|.|:|::..  .||.. |.|....||:||:|:|.||.|
Zfish   307 SLGSMIKN--LTSERANTIAAALGQIPQKVVWRYSG--KTPETLAPNTKIYDWIPQNDLLGHPKT 367

  Fly   362 KLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVL 426
            |.|:||.|...:.|:.|||||||.||:|.|.|.|...|...|..|.||:.|:......:|:..||
Zfish   368 KAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVL 432

  Fly   427 ENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGFVELHNLDIYALVL 491
            .|..|.:::.:.|.::.|:|:.|....::|:::|:|:.||.:|:..|..:.:.:.|.||:.|.:|
Zfish   433 NNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLL 497

  Fly   492 AILIFLVFLTRLTVKFLFSKLLGKAKVPARKKKQ 525
            :|...:.||......|||.:.:.|.: |.||.::
Zfish   498 SIAALITFLWVKACCFLFRRCVRKTR-PERKTQK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.2	Glycosyltransferase_GTB-type	39..517	CDD:471961	137/503 (27%)
ugt2a2	NP_001018306.2	UDPGT	23..521	CDD:278624	142/520 (27%)