Protein Alignment Ugt37C1 and Ugt2a2

DIOPT Version :10

• Sequence 1: NP_525007.2
• Gene: Ugt37C1 / 53583
• FlyBaseID: FBgn0026754
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 537
• Identity: 144/537 - (26%)
• Similarity: 269/537 - (50%)
• Gaps: 51/537 - (9%)

  Fly     8 SAIVWLLAVASPSQGANILGVYSALSPSHLIIHMSTAKALAEAGHNVTVVSMMQPKVMHKDIHLI 72
            :.:||      |:.|::.|.:...|            :.|.:..|:|||::..:...::..:...
Mouse    23 NVVVW------PTDGSHWLNIKILL------------EELVQRNHSVTVLAPSETLFINSRLDAF 69

  Fly    73 V----VPV--TKEQ-ERTLENQMASMAGSKNNIIT--TMYLLL-NGLDVMVTSQADL----LKDP 123
            :    :||  ||.: :..:|:.:|.....:...:|  |.|..| |.|....|:...:    |.:|
Mouse    70 INFEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNP 134

  Fly   124 R-FQRVFETKFDLMILGSFFNDFQLGVAGKLKVPVIVDWMI-PSNTMIDEFVANPSEVSYVPNES 186
            . .:|:.:..||:::........:| ||.||.:|.:..... |:.|:.......|:.:||||...
Mouse   135 TVMERLQKGGFDVLLADPVTMCGEL-VALKLGIPFVYTLRFSPAFTVERHCGKIPAPISYVPAAL 198

  Fly   187 TFATTPMSFFKRAENLVKHVILKYLTIRFNYKFNRIYNEIFTDKDMP-TLSEMKKNISMVFVGSH 250
            :..|..|||.:|.:|::.:.:..|:...:..::|..|:::.   ..| ||.|......:..:.::
Mouse   199 SELTDQMSFGERVKNIISYSLQDYIFKTYWGEWNSYYSKVL---GRPTTLCETMGKAEIWLMRTY 260

  Fly   251 LISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENSSQ-GAIFLSFGSNIKSYMVKPEIVG 314
            ...:.| ||.:|....|||:..| ...|||:::|:|::.|.: |.:..|.||.:|:  :..|...
Mouse   261 WDFEFP-RPYLPNFEFVGGLHCK-PAKPLPKEMEEFVQTSGEHGIVVFSLGSMVKN--LTDEKAN 321

  Fly   315 IMFKVLSGLKQNVIWKWE-DLENTPGNASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQY 378
            ::...|:.:.|.|:|::: .:.:|.|:.:.:|  ||:||:|:|.||.|:.|:||.|...|.|:.|
Mouse   322 LIASALAQIPQKVLWRYKGKIPDTLGSNTRLF--DWIPQNDLLGHPKTRAFITHGGTNGIYEAIY 384

  Fly   379 HGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYR 443
            ||:|||.:|:|.|.|.|.|.|...|..|.:::.|:|......|:..|:....|.:...:.|.::.
Mouse   385 HGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHH 449

  Fly   444 DRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGFVELHNLDIYALVLAILIFLVFLTRLTVKFL 508
            |:|:.|....:||:::|:||.||.:|:..|..:.:.:.|:||:...:||.:...:.|......|:
Mouse   450 DQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFI 514

  Fly   509 FSKLLGKAKVPARKKKQ 525
            |.| :||.   .:|||:
Mouse   515 FQK-VGKT---GKKKKR 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.2	Glycosyltransferase_GTB-type	39..517	CDD:471961	135/496 (27%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	137/520 (26%)