Protein Alignment Ugt37C1 and UGT1A10

DIOPT Version :9

• Sequence 1: NP_525007.1
• Gene: Ugt37C1 / 53583
• FlyBaseID: FBgn0026754
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_061948.1
• Gene: UGT1A10 / 54575
• HGNCID: 12531
• Length: 530
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 148/529 - (27%)
• Similarity: 247/529 - (46%)
• Gaps: 94/529 - (17%)

  Fly     2 STAKALAEAGHNVTVVSMMQPKV---MHKDIHLIVVPVTKEQERTLENQ---------------- 47
            |..:.|...||.|.||   .|:|   :.:.::..|  .|.....|||:|
Human    43 SVVEKLILRGHEVVVV---MPEVSWQLERSLNCTV--KTYSTSYTLEDQNREFMVFAHAQWKAQA 102

  Fly    48 -------MASMAGSKNNIITTMYLLLNGLDVMVTSQADLLKDPRFQRVFETKFDL--MILGSFFN 103
                   |:|.:|..:...:....|.|...::     :.||:..|..||...||.  :|:..:|:
Human   103 QSIFSLLMSSSSGFLDLFFSHCRSLFNDRKLV-----EYLKESSFDAVFLDPFDTCGLIVAKYFS 162

  Fly   104 DFQLGVAGKLKVPVIVDWMIPSNTM--------IDEFVANPSEVSYVPNESTFATTPMSFFKRAE 160
                               :||...        ::|....|:.:|||||:....:..|:|.:|..
Human   163 -------------------LPSVVFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVW 208

  Fly   161 N----LVKHVILKYLTIRFNYKFN---RIYNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGPIR 218
            |    |..|:..:||       |.   .|.:||.  :...|..::..:.|:..:.:..:.|.| :
Human   209 NHIVHLEDHLFCQYL-------FRNALEIASEIL--QTPVTAYDLYSHTSIWLLRTDFVLDYP-K 263

  Fly   219 PLVPAIIEVGGIQVKEQPDPLPQDIEQFMENSSQ-GAIFLSFGSNIKSYMVKPEIVGIMFKVLSG 282
            |::|.:|.:|||.. .|..|||.:.|.::..|.: |.:..|.||.:.....|..:.  :...|..
Human   264 PVMPNMIFIGGINC-HQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMA--IADALGK 325

  Fly   283 LKQNVIWKWEDLENTPGN-ASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVAL 346
            :.|.|:|::..  ..|.| |:|.....||||:|:|.||.|:.|:||||...:.||..:|||||.:
Human   326 IPQTVLWRYTG--TRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMM 388

  Fly   347 PIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQ 411
            |:|||...||..|...|.||:|::..:|.:....|:..|:.:..|.:.:.:.|:|::|||:.|..
Human   389 PLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLD 453

  Fly   412 SVLFWVDYVLRHHGAPNLQSPAVH-MGFVELHNLDIYALVLAILIFLVFLTRLTVKFLFSKLLGK 475
            ..:|||::|:||.|||:|: ||.| :.:.:.|:||:...:||:::.:.|:|.....:.:.|.|||
Human   454 LAVFWVEFVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGK 517

  Fly   476 AKVPARKKK 484
               ..|.||
Human   518 ---KGRVKK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	145/520 (28%)
		egt	6..433	CDD:223071	130/471 (28%)
UGT1A10	NP_061948.1	UDPGT	26..521	CDD:278624	145/525 (28%)
		egt	<258..504	CDD:223071	88/252 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150392
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740