DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C1 and Ugt37C2

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	329/485 - (67%)
Similarity:	407/485 - (83%)	Gaps:	0/485 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTAKALAEAGHNVTVVSMMQPKVMHKDIHLIVVPVTKEQERTLENQMASMAGSKNNIITTMYLL 65
            ||.||||.:||||||||||::|||.||||||||||:.:||||.:|:||..|||.||::::|||.|
  Fly    39 MSVAKALVKAGHNVTVVSMLKPKVTHKDIHLIVVPMKEEQERIMEDQMTEMAGQKNSLVSTMYRL 103

  Fly    66 LNGLDVMVTSQADLLKDPRFQRVFETKFDLMILGSFFNDFQLGVAGKLKVPVIVDWMIPSNTMID 130
            |..:|||:.:||:||.||||||::||||||||||.|.||||||||.|||||||::||......||
  Fly   104 LTSMDVMINAQAELLSDPRFQRIYETKFDLMILGYFINDFQLGVAHKLKVPVIINWMSAPVPAID 168

  Fly   131 EFVANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNYKFNRIYNEIFTDKDMPTL 195
            ::..||||:||||...|.||.||.|.||.||.:|.::.:::.:.|:||..||||::|.::|||||
  Fly   169 KYTGNPSELSYVPLMGTVATQPMGFLKRTENALKSLLFEFIFVVFDYKLTRIYNDVFPEQDMPTL 233

  Fly   196 SEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENSSQGAIFLSFG 260
            .|::|||||.||||||||:|||||||||:||:||||||::|||||:||:||:.|:.|||:|||.|
  Fly   234 KELRKNISMAFVGSHLISEGPIRPLVPALIEIGGIQVKDKPDPLPKDIDQFISNAKQGAVFLSLG 298

  Fly   261 SNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTPGNASNIFYKDWLPQDDILAHPNTKLFV 325
            ||:||..|:||||.|:|||||.||:|||||||||||||||:|||.||:||||||||||||||||:
  Fly   299 SNVKSSTVRPEIVQIIFKVLSELKENVIWKWEDLENTPGNSSNILYKNWLPQDDILAHPNTKLFI 363

  Fly   326 THAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVLENDK 390
            ||||||.|||:|||||||||||||||.|.|||||..||||::|||.:||||:.|:|:.|||||.|
  Fly   364 THAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSITEDSLRDALKEVLENQK 428

  Fly   391 YTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGFVELHNLDIYALVLAILI 455
            |.||:.:||.||||||:|.:|||:||.:|:|||.||||||||:|||.|::|:|||||||::.||:
  Fly   429 YKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDIYALIVTILV 493

  Fly   456 FLVFLTRLTVKFLFSKLLGKAKVPARKKKQ 485
            ..|.||||..|.:::|..||||:...||||
  Fly   494 LFVLLTRLVAKIVWNKFGGKAKISQTKKKQ 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	323/475 (68%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	295/426 (69%)
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	295/427 (69%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	323/475 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445646
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BZ0V
Homologene	1	1.000	-	-		H86211
Inparanoid	1	1.050	83	1.000	Inparanoid score	I2351
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D51205at7147
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	12	11.800