DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C1 and Ugt35C1

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001097744.1	Gene:	Ugt35C1 / 53507	FlyBaseID:	FBgn0040256	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	481	Identity:	158/481 - (32%)
Similarity:	258/481 - (53%)	Gaps:	23/481 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STAKALAEAGHNVTVVSMMQPKVMHKDIHLIVVPVTKEQERTLENQMASMAGSKNNIITTMYLLL 66
            |..||||..||.|||::..:.|   :..::..:...|..|  ..::|.|:..     :..::..|
  Fly    43 SYLKALAAKGHQVTVINAFKNK---ETPNMRFIEALKAHE--FADEMMSLLN-----VPLLWQQL 97

  Fly    67 NGLDVMVTSQADL-LKDPRFQRVFET--KFDLMILGSFFNDFQLGVAGKLKVPVIVDWMIPSNTM 128
            |.:|.::....|: ::|...||:..:  .|||::......:.....|......::......::..
  Fly    98 NAMDYILNKFIDVTMEDEGVQRLLNSGETFDLVLAEMLHMEPMYAFAQHFNATLVGFSSFGTDRT 162

  Fly   129 IDEFVANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNY--KFNRIYNEIFTDKD 191
            |||...|.|.:||.|..::..|..|:|.:|.||..: ||::.:...|.:  ....:|.:.|.:.
  Fly   163 IDEAAGNISPISYNPLVTSPRTDRMTFLERLENHYE-VIVEDIHRHFVHLPHMRNVYKKYFPNA- 225

  Fly   192 MPTLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENSSQGAIF 256
            ..||.|:..:.|::.:|.|.....| ||.:|.:|||||:.:..:|.|||:||:||:|.|..|.|:
  Fly   226 KKTLEEVMDSFSLILLGQHFSLSYP-RPYLPNMIEVGGMHISHKPKPLPEDIKQFIEGSPHGVIY 289

  Fly   257 LSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTPGNASNIFYKDWLPQDDILAHPNT 321
            .|.|||:||..:..|....:.|..:.|||.|:||:|| ::.||..:|:..|.|.||.|||||||.
  Fly   290 FSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFED-DDMPGKPANVLIKKWYPQPDILAHPNV 353

  Fly   322 KLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVL 386
            |||::|.|..|.|||.|.|.|::.||.|.|..:|.......|:|:.|||..:.::...:||..:|
  Fly   354 KLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLL 418

  Fly   387 ENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGFVELHNLDIYALVL 451
            .:..|.:|....|..|||:|.:.....::|.:||:||:|||:|::.:..:.|::|::||..|::|
  Fly   419 TDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVIL 483

  Fly   452 AILIFLVFLTRLTVKFLFSKLLGKAK 477
            |:.:.|..|    :..|..||||..|
  Fly   484 AVPLLLALL----IVTLSCKLLGGKK 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	157/479 (33%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	141/431 (33%)
Ugt35C1	NP_001097744.1	egt	1..470	CDD:223071	143/440 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	7.920