DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C1 and Ugt304A1

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_652619.1	Gene:	Ugt304A1 / 53501	FlyBaseID:	FBgn0040250	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	493	Identity:	122/493 - (24%)
Similarity:	237/493 - (48%)	Gaps:	75/493 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KALAEAGHNVTVVSMMQPKVMHKDIHLIVVPVTKEQERTLENQMASMAGSKNN---IITTMYLLL 66
            :||.:.||.:||:...: ..|||...:..:.:.......||.:.:....|.||   .|::|..|
  Fly    47 QALKDRGHQLTVIHAYK-HCMHKIEDVTFIRIWYNNNVFLEFEESVGIASANNKWEEISSMSSL- 109

  Fly    67 NGLDVMVTSQADLLKDPRFQRVFETK--FDLMILGSFFNDFQLGVAGKLKVPVI------VDWMI 123
                 |..:..::|.:...:.:.:::  ||.::|.:.::|...|:|......:|      .||.|
  Fly   110 -----MANATLNVLNNVEVRALMKSRITFDAVVLEAGYSDVLYGMAAHFSAQLIGICTCVADWNI 169

  Fly   124 PSNTMIDEFVANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNYKFNRIYNEIFT 188
              |.::..            :.||.....|.|  ||: .||:|            ::||||.::|
  Fly   170 --NNLVGF------------STSTLTEPIMPF--RAK-YVKNV------------WDRIYNWLYT 205

  Fly   189 DKD--------MP---------------TLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGI 230
            .::        :|               :..|::::.:::.:..| .|....||.||.::||.|:
  Fly   206 TEEWLLINLVFLPKQRLIHDHFFGHLEKSFHEIRQDFALMLLNQH-FSLFRARPNVPGMVEVAGL 269

  Fly   231 QVKEQPDPLPQDIEQFMENSSQGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLE 295
            .:.::...||.|::.|::.:..|.|..|.|....|..:..:...|:.:....:.|.||||: |.|
  Fly   270 HIPKEDPQLPSDLQVFIDEAEHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQRVIWKF-DGE 333

  Fly   296 NTPGNASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMV 360
            :|....::|::...|||..||||||.|||::|.|..|:.|:.|:..|::.||.|.|...|..:|.
  Fly   334 STMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMK 398

  Fly   361 NSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHG 425
            ..|..:.|::.::|....::||:.::...:|.::....|..:||:|:.|..:.::|.:|::|:.|
  Fly   399 EEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYKG 463

  Fly   426 APNLQSPAVHMGFVELHNLDIYALV---LAILIFLVFL 460
            |.:::.....:...:.::||.:.:|   |::::.||||
  Fly   464 ADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFL 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	122/493 (25%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	114/460 (25%)
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	114/470 (24%)
Ugt304A1	NP_652619.1	YjiC	42..445	CDD:224732	107/435 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445744
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	7.850