DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C1 and Ugt303B2

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	134/500 - (26%)
Similarity:	227/500 - (45%)	Gaps:	87/500 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KALAEAGHNVTVVSMMQPKVMHKDIHLIVVPVTKEQERTL--ENQMASMAGSK---NNIITTMY- 63
            |||.|.||.||:|:..........:..|.||:..:..:.|  .:|.....|.|   ..:::|::
  Fly    48 KALVERGHKVTMVTPADYPAKIDGVRHIRVPMLNQLMQNLMKNDQFFDALGDKWREGVLVSTIFY 112

  Fly    64 ----LLLNGLDVMVTSQADLLKDPRFQRVFETKFDLMI-----------LGSFFNDFQLGV---- 109
                .:||...|.:     |::|.      ..:||:::           |..|:|...||:
  Fly   113 NVSHAILNNNGVQM-----LMRDK------SIRFDMIMVEASHLDALYGLAEFYNATLLGISCMH 166

  Fly   110 --------AGKLKVPVIVDWMIPSNTMIDE-FVANPSEVSYVPNESTFATTPMSFFKRAENLVKH 165
                    ||.| .|.:.:.:.|:...:|. |::..|...|:..               |.|::.
  Fly   167 MTWHIDYLAGNL-APSVYEPISPNGFALDNTFLSRWSNWIYITE---------------EKLLER 215

  Fly   166 VILKYLTIRFNYKFNRIYNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGI 230
            ::.:...:|...||.....|        .|.|::...|::.|.|| .|.|.:|..||.||||.|:
  Fly   216 LVFRPAQVRLFKKFFGYPAE--------KLDELRARFSVILVNSH-FSMGRVRANVPNIIEVAGV 271

  Fly   231 QVKEQPDPLPQDIEQFMENSSQGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLE 295
            .:.|.|:|...:::::::.:..|||:.|.|.:|....:...:...:..|...:||.|||| .:|.
  Fly   272 HLSEPPEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWK-SELS 335

  Fly   296 NTPGNASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMV 360
            .....:.||:..|.:||..:|||||.:||:||.|..|:.|:..:||||:.||:|.|...|...:.
  Fly   336 MLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQ 400

  Fly   361 NSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHG 425
            .:|....||...:..||..|.|.|:|||..|.|..::.:|.:||||::|..:.::|.:|.||:..
  Fly   401 LAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRD 465

  Fly   426 APNLQSPAVHMGFVELHNLDIYALVLAILIF----------LVFL 460
            ..:::.....:..:..:.||      :||.|          |:||
  Fly   466 TSHMRLNVEEIPLMRYYRLD------SILTFGVRLGCVCGSLIFL 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	133/499 (27%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	125/460 (27%)
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	126/452 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445741
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.850