Protein Alignment Ugt37C1 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_525007.2
• Gene: Ugt37C1 / 53583
• FlyBaseID: FBgn0026754
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_958826.1
• Gene: Ugt1a2 / 396527
• RGDID: 1549741
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 564
• Identity: 156/564 - (27%)
• Similarity: 264/564 - (46%)
• Gaps: 91/564 - (16%)

  Fly     8 SAIVWLLAVASPSQGANILGVYSALSPSHLIIHMSTAKALAEAGHNVTVVSMMQPKVMHKDIHL- 71
            |.::.||.....::|..:| |: .:..||.:......:.|...||...|::   |:|   .:|:
  Rat    13 SGLLLLLCALPWAEGGKVL-VF-PMEGSHWLSMRDVVRELHARGHQAVVLA---PEV---TVHMK 69

  Fly    72 ---------IVVPVTKEQERTLENQMASMAGSK---------NNIITTMYLLLNGLDVMVTSQAD 118
                     ...|.|||     |.|...:..:|         .....||..:....|:...|.|.
  Rat    70 GEDFFTLQTYAFPYTKE-----EYQREILGNAKKGFEPQHFVKTFFETMASIKKFFDLYANSCAA 129

  Fly   119 LLKDPR-FQRVFETKFDLMILGSFFNDFQLGVAGKLKVPVI---------VDWMIPSNTMIDEFV 173
            ||.:.. .|::..:.||:::....|....| :|..|::|.:         :|:         |..
  Rat   130 LLHNKTLIQQLNSSSFDVVLTDPVFPCGAL-LAKYLQIPAVFFLRSVPCGIDY---------EAT 184

  Fly   174 ANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNYKFNRIYNEIFTDKDMPTLSEM 238
            ..|...||:||..|..:..|:|.:|.:|::..:.|||:.......:..:.:|:           :
  Rat   185 QCPKPSSYIPNLLTMLSDHMTFLQRVKNMLYPLTLKYICHLSITPYESLASEL-----------L 238

  Fly   239 KKNISMVFVGSH---------LISDGPIRPLVPAIIEVGGIQ--VKEQPDPLPQDIEQFMENSSQ 292
            ::.:|:|.|.||         .:.|.| ||::|.::.:|||.  :|:   ||.|:.|.::..|.:
  Rat   239 QREMSLVEVLSHASVWLFRGDFVFDYP-RPIMPNMVFIGGINCVIKK---PLSQEFEAYVNASGE 299

  Fly   293 -GAIFLSFGSNIKSYMVKP--EIVGIMFKVLSGLKQNVIWKWEDLENTPGN-ASNIFYKDWLPQD 353
             |.:..|.||.:.....|.  ||.    :.|..:.|.|:|::..  ..|.| |.|.....||||:
  Rat   300 HGIVVFSLGSMVSEIPEKKAMEIA----EALGRIPQTVLWRYTG--TRPSNLAKNTILVKWLPQN 358

  Fly   354 DILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTF 418
            |:|.||..:.|:||:|...|.|...:|||||.:|:|||...||..|...|.||:|::..:|.|..
  Rat   359 DLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDL 423

  Fly   419 REAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVH-MGFVELH 482
            ..|:..|:.|..|.:.:.:.|:|::|||:.|....:|||:||:||.|||:|: ||.| :.:.:.|
  Rat   424 ENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYH 487

  Fly   483 NLDIYALVLAILIFLVFLTRLTVKFLFSKLL-GKAKVPARKKKQ 525
            :||:...:|||::.:||:...:..:...|.. ||.:|....|.:
  Rat   488 SLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.2	Glycosyltransferase_GTB-type	39..517	CDD:471961	146/523 (28%)
Ugt1a2	NP_958826.1	UDPGT	28..524	CDD:278624	150/540 (28%)