Protein Alignment Ugt37C1 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_525007.2
• Gene: Ugt37C1 / 53583
• FlyBaseID: FBgn0026754
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_964007.2
• Gene: Ugt1a1 / 394436
• MGIID: 98898
• Length: 535
• Species: Mus musculus
• Alignment Length: 542
• Identity: 155/542 - (28%)
• Similarity: 263/542 - (48%)
• Gaps: 55/542 - (10%)

  Fly    13 LLAVASPSQG-ANILGVYSALSPSHLIIHMSTAKALAEAGHNVTVVSMMQPKVMHKDIHL----- 71
            ||.|..||.. |..|.|: .:..||.:..:...:.|.:.||.|.|::   |:.   .||:
Mouse    18 LLCVFGPSASHAGRLLVF-PMDGSHWLSMLGVIQQLQQKGHEVVVIA---PEA---SIHIKEGSF 75

  Fly    72 -----IVVPVTKEQERTLENQMASMAGSKNNI---ITTMYL-LLNGLDVMVTSQADLLKDPRFQ- 126
                 ..||..||.......::...|.::::.   :..:|: :.....:::...:.||.:..|.
Mouse    76 YTLRKFPVPFQKENVTATLVELGRTAFNQDSFLLRVVKIYMKVKRDSSMLLAGCSHLLHNAEFMA 140

  Fly   127 RVFETKFDLMILGSFFNDFQLGVAGKLKVPVIVDWMIPSNTMIDEFVANPSEVSYVPNESTFATT 191
            .:.|:.||.::...|.....: ||..|.||.:........::..|....|..:||||...:|.:.
Mouse   141 SLEESHFDALLTDPFLPCGSI-VAQYLTVPTVYFLNKLPCSLDSEATQCPVPLSYVPKSLSFNSD 204

  Fly   192 PMSFFKRAENLVKHVILKYLTIRFNYKFNRIYN-------EIFTDKDMPTLSEMKKNISMVFVGS 249
            .|:|.:|.:|::       |.:..|:....:|:       ||. .|:: |:.::....|:..:.|
Mouse   205 RMNFLQRVKNVL-------LAVSENFMCRVVYSPYGSLATEIL-QKEV-TVQDLLSPASIWLMRS 260

  Fly   250 HLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENSSQ-GAIFLSFGSNIKSYMVKP--E 311
            ..:.|.| ||::|.::.:|||... |..||.|:.|.::..|.: |.:..|.||.:.....|.  |
Mouse   261 DFVKDYP-RPIMPNMVFIGGINCL-QKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAME 323

  Fly   312 IVGIMFKVLSGLKQNVIWKWEDLENTPGN-ASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITE 375
            |.    :.|..:.|.|:|::..  ..|.| |.|.....||||:|:|.||.|:.|:||:|...|.|
Mouse   324 IA----EALGRIPQTVLWRYTG--TRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYE 382

  Fly   376 SQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSA 440
            ...:|||||.:|:|||...||..|...|.||:|::..:|.|....|:..|:.|..|.:.:.:.|:
Mouse   383 GICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSS 447

  Fly   441 LYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVH-MGFVELHNLDIYALVLAILIFLVFLTRLT 504
            |::|||:.|....:|||:||:||.|||:|: ||.| :.:.:.|:||:...:|||::.:||:....
Mouse   448 LHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKC 511

  Fly   505 VKFLFSKLL-GKAKVPARKKKQ 525
            ..:...|.. ||.:|....|.:
Mouse   512 CAYGCRKCFGGKGRVKKSHKSK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.2	Glycosyltransferase_GTB-type	39..517	CDD:471961	143/505 (28%)
Ugt1a1	NP_964007.2	UDPGT	30..526	CDD:278624	147/521 (28%)