Protein Alignment Ugt37C1 and Ugt1a6b

DIOPT Version :10

• Sequence 1: NP_525007.2
• Gene: Ugt37C1 / 53583
• FlyBaseID: FBgn0026754
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_958812.3
• Gene: Ugt1a6b / 394435
• MGIID: 3580629
• Length: 531
• Species: Mus musculus
• Alignment Length: 556
• Identity: 158/556 - (28%)
• Similarity: 268/556 - (48%)
• Gaps: 85/556 - (15%)

  Fly    10 IVWLLAVASPSQGANILGVYSALSP---SHLIIHMSTAKALAEAGHNVTV----VSMMQPKVMHK 67
            ::|          |::||....:.|   ||.:......:.|:|.||::.|    |:::..:..:.
Mouse    19 VLW----------ASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYY 73

  Fly    68 DIHLIVVPVTKEQERTL-----ENQ-------MASMAGSKNNIITTMYLLLNGLDVMVTSQADLL 120
            ...:..||.:.|:.:|.     .||       |..:...:|:::|        |::..::...||
Mouse    74 RRKIFSVPYSLEELQTRFRTFGRNQFVPGAPLMGPLREYRNSMLT--------LEMFFSNCQSLL 130

  Fly   121 KDP---RFQRVFETKFDLMILGSFFND--FQLGVAGKLKVPVIVDWM-IPSNTMIDEFVA----- 174
            ||.   .|.|  |.|||     :.|.|  ...||       ::.::: :||..:...|..
Mouse   131 KDSATLSFLR--ENKFD-----ALFTDPAMPCGV-------ILAEYLNLPSVYLFRGFPCSLEHM 181

  Fly   175 ---NPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNYKFNRIYNEIF-TDKDMPTL 235
               :||.|||||...|..:..|:|.:|..|.:.:::..||......|:..|..::. .|..:|:|
Mouse   182 LGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYEIIVTDLLKRDVSLPSL 246

  Fly   236 SEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENSSQ-GAIFLSF 299
            .:.    |:..:....:.:.| ||::|.:|.:|||..|:: ..|.|:.|.::..|.: |.:..|.
Mouse   247 HQN----SLWLLRYDFVFEYP-RPIMPNMIFIGGINCKKK-GKLTQEFEAYVNASGEHGIVVFSL 305

  Fly   300 GSNIKSYMVKP--EIVGIMFKVLSGLKQNVIWKWEDLENTPGN-ASNIFYKDWLPQDDILAHPNT 361
            ||.:.....|.  ||.    :.|..:.|.|:|::..  ..|.| |.|.....||||:|:|.||.|
Mouse   306 GSMVSEIPEKKAMEIA----EALGRIPQTVLWRYTG--TRPSNLAKNTILVKWLPQNDLLGHPKT 364

  Fly   362 KLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVL 426
            :.|:||:|...|.|...:|||||.:|:|||...||..|...|.||:|::..:|.|....|:..|:
Mouse   365 RAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVI 429

  Fly   427 ENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVH-MGFVELHNLDIYALV 490
            .|..|.:.:.:.|:|::|||:.|....:|||:||:||.|||:|: ||.| :.:.:.|:||:...:
Mouse   430 NNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFL 493

  Fly   491 LAILIFLVFLTRLTVKFLFSKLL-GKAKVPARKKKQ 525
            |||::.:||:......:...|.. ||.:|....|.:
Mouse   494 LAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.2	Glycosyltransferase_GTB-type	39..517	CDD:471961	149/514 (29%)
Ugt1a6b	NP_958812.3	UDPGT	27..522	CDD:278624	152/529 (29%)