DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C1 and Ugt36D1

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	157/485 - (32%)
Similarity:	247/485 - (50%)	Gaps:	54/485 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KALAEAGHNVTVVSMMQPKVMHKDIHLIVVPVTKEQERTLENQMASMAGSKNNIIT---TMYLLL 66
            |.||||||:|:|||....|  |...|....|:|...:  |.|.:......|....:   ..:||.
  Fly    50 KGLAEAGHDVSVVSHFPDK--HPVAHYKDFPLTGMDK--LTNSVDLKFFEKRTFYSHFQEFFLLY 110

  Fly    67 N----GLDVMVTSQA--DLLKDPRFQRVFETKFDLMILGSFFNDFQLGVAGKLKVPVIVDWMIPS 125
            :    ..::.:.|:|  .:|:.|       .:||::|:..|..|..:|||.:|:.|||.   :.|
  Fly   111 DWGKQTCNLTLRSEALQQILRRP-------GRFDVIIMEQFNTDCMMGVAHQLQAPVIA---LSS 165

  Fly   126 NTMID---EFVANPSEVSYVPNESTFATTPMSFFKRAEN-LVKHVI---LKYLTI-----RFNYK 178
            ..|:.   |.:..|...|::|......:..|:|..|..| ...|.:   .|.|::     ...||
  Fly   166 CVMMPWHYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYK 230

  Fly   179 FNRIYNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGP-IRPLVPAIIEVGGIQVKEQPDPLPQD 242
            |..         |:|::.|:.||.||.||..|....|| :.|  |.:||:|||.: ::..|||.|
  Fly   231 FGH---------DVPSVGELVKNTSMFFVNQHYSLSGPKVTP--PNVIELGGIHI-QKSKPLPAD 283

  Fly   243 IEQFMENSSQGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTPGNASNIFYK 307
            :::.::|:.:|.|.:|:||.|::..:.......:.:.::.|||.||||||: |..|....|:...
  Fly   284 LQRILDNAEEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWEN-ETLPNQPPNMHIM 347

  Fly   308 DWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQT 372
            .||||.|||.|||.|:|::|.|....:|:.|.|||:||.|::||..:|.|.:|..|.|..|:.:.
  Fly   348 KWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFED 412

  Fly   373 ITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMG 437
            |.|:|...|:.:.|:. |:..|.:..|..:..||.....:.::||::|....|||.|:..||.|.
  Fly   413 IGENTVMRALKKALDK-KFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMS 476

  Fly   438 FVELHNLDIY---ALVL-AILIFLVFLTRL 463
            ....::||:|   |||| :|:...|:|.||
  Fly   477 RFVYYSLDVYAVLALVLGSIIASWVWLLRL 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	157/485 (32%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	141/448 (31%)
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	145/459 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454605
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	7.840