DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C1 and Ugt301D1

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	479	Identity:	148/479 - (30%)
Similarity:	245/479 - (51%)	Gaps:	54/479 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LAEAGHNVTVVSMMQPKVMHKDIHLIVVPVTKEQERTLENQMASMAGSKNNIITTMYLL-LNGLD 70
            |...||:||.|:....|..|:::..|::..:.:..:..         .|.||.:..::. .|.|:
  Fly    49 LLRQGHHVTSVNNHPTKHPHENLTEIIISPSFDIPKHF---------PKENIFSMQFVSDFNNLE 104

  Fly    71 ------VMVTSQADLLKDPRFQRVFETK---FDLMILGSFFNDFQLGVAGKLKVPVIVDWMIPSN 126
                  :|.|..|  .|||:.:::.|:|   :||:|:..||::..|....:...||:....:...
  Fly   105 LWWTIGLMTTEHA--FKDPKVKKLIESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYA 167

  Fly   127 TMIDEFVANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTI------RFNY--KFNRIY 183
            ..||..:...:..|.:|:.....|..|:|.:||.|       .||::      |:.|  |..::.
  Fly   168 DNIDHAMGILTPWSLIPHLLLSHTDRMTFGQRAYN-------AYLSLYDAVMRRWVYLPKMQKLA 225

  Fly   184 NEIF---TDKDMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQ 245
            .:.|   .:..:|.:.::::|||:|.:.:|...|.| ||.:|.:|:|||..: ::|..||.|::.
  Fly   226 EKYFQGSIEGPLPNVLDLERNISLVLINAHRSIDLP-RPSMPGLIDVGGAHI-QKPKQLPTDLQN 288

  Fly   246 FMENSSQGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWED--LENTPGNASNIFYKD 308
            |::|::.|.|:.|.||.:||..:..|...::.|....|||.||||:|:  :.:.|   ||:..|.
  Fly   289 FLDNATYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLP---SNVMIKK 350

  Fly   309 WLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTI 373
            |:||:|||||||.|||:||.|.....|..|.||||:.:|::||...|....|..||..||....:
  Fly   351 WMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKL 415

  Fly   374 TEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGF 438
            |.|.....|..::.:.:|.::..:.|..:||.|:.|.....||::|::||.||.:|:|   |..|
  Fly   416 TTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKS---HGAF 477

  Fly   439 VELHNLDIYAL--VLAILIFLVFL 460
            :.||.   |.|  ||..|:...||
  Fly   478 IPLHQ---YLLLDVLGCLLLGAFL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	148/479 (31%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	137/448 (31%)
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	141/462 (31%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	141/462 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	7	6.910