DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C1 and Ugt2b17

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_775417.1	Gene:	Ugt2b17 / 286954	RGDID:	708541	Length:	529	Species:	Rattus norvegicus

Alignment Length:	505	Identity:	126/505 - (24%)
Similarity:	243/505 - (48%)	Gaps:	47/505 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LAEAGHNVTVV-----SMMQP-KVMHKDIHLIVVPVTKEQERTLENQMASMAGSKNNIITTM--Y 63
            ||:.||.|||:     .:::| |....:..:..||::|..   ||...|...........|:  :
  Rat    46 LAQRGHEVTVLVSSASILIEPTKESSINFEIYSVPLSKSD---LEYSFAKWIDEWTRDFETLSIW 107

  Fly    64 LLLNGLDVMVTSQADLLKD---------PRFQRVFETKFDLMILGSFFNDFQLGVAGK-----LK 114
            ...:.:..:....:|::::         ...:::..::||:::..:      :|..|:     ||
  Rat   108 TYYSKMQKVFNEYSDVVENLCKALIWNKSLMKKLQGSQFDVILADA------VGPCGELLAELLK 166

  Fly   115 VPVIVDWMIPSNTMIDEFVAN-PSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNYK 178
            .|::...........::|... |...||||...:..:..|:|.:|.:|:::.:...:....|..|
  Rat   167 TPLVYSLRFCPGYRCEKFSGGLPLPPSYVPVVLSELSDRMTFVERVKNMLQMLYFDFWFQPFKEK 231

  Fly   179 -FNRIYNEIFTDKDMP-TLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQ 241
             :::.|:::.   ..| ||:||.....:..:.:....:.| .|.:|....|||:..| ...|||:
  Rat   232 SWSQFYSDVL---GRPTTLTEMMGKADIWLIRTFWDLEFP-HPFLPNFDFVGGLHCK-PAKPLPR 291

  Fly   242 DIEQFMENSSQ-GAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTPGNASNIF 305
            ::|:|:::|.: |.:..|.||.:|:  :..|...::...|:.:.|.|:|:::..:.....::...
  Rat   292 EMEEFVQSSGEHGVVVFSLGSMVKN--LTEEKANVVASALAQIPQKVVWRFDGKKPDTLGSNTRL 354

  Fly   306 YKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDL 370
            || |:||:|:|.||.||.||.|.|...|.|:.|||:|:|.:|:|.|.|.|...||..|..|.:|.
  Rat   355 YK-WIPQNDLLGHPKTKAFVAHGGTNGIYEAIYHGIPIVGIPLFADQPDNINHMVAKGAAVRVDF 418

  Fly   371 QTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVH 435
            ..::......|:..|:.:..|.:...:.|.::.|:|:.|....:||::||:||.||.:|:|....
  Rat   419 SILSTTGLLTALKIVMNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEYVMRHKGAKHLRSTLHD 483

  Fly   436 MGFVELHNLDIYALVLAILIFLVFLTRLTVKFLFSKLLGKAKVPARKKKQ 485
            :.:.:.|:||:...:|..::.:||:......|...|.....|    |||:
  Rat   484 LSWFQYHSLDVIGFLLLCVVGVVFIITKFCLFCCRKTANMGK----KKKE 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	122/495 (25%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	114/451 (25%)
Ugt2b17	NP_775417.1	UDPGT	24..527	CDD:278624	123/501 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810