Protein Alignment Ugt37C1 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_525007.2
• Gene: Ugt37C1 / 53583
• FlyBaseID: FBgn0026754
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 553
• Identity: 157/553 - (28%)
• Similarity: 268/553 - (48%)
• Gaps: 69/553 - (12%)

  Fly     8 SAIVWLLAVASPSQGANILGVYSALSPSHLIIHMSTAKALAEAGH-NVTVVSMMQPKVMHKDIHL 71
            |.::.||.....::||.:|.:  .:..|..:......:.|...|| .|.:.|.:...:..:|...
Mouse    13 SGLLLLLCALPWAEGAKVLVL--PMEGSQWLSMRDVVRELHARGHQTVVLASEVTVHIKGEDFFT 75

  Fly    72 I---VVPVTKEQ---------ERTLENQMASMAGSKNNIITTMYLLLNGLDVMVTSQADLLKDPR 124
            :   ..|.|||:         |:|.:.|....|     ...|...:.|..|:...|...||.:..
Mouse    76 LKTYAFPYTKEEYQQEILSDIEKTFKTQHFVKA-----FFETTASIRNFFDLYSNSCIALLHNKM 135

  Fly   125 -FQRVFETKFDLMILGSFFNDFQLG--VAGKLKVPVIVDWMIPSNTMIDEFVA----NPSEVSYV 182
             .|::..:.||:::....   |..|  :|..|::|.:  :::.|.:...|:.|    |||  ||:
Mouse   136 LIQQLNSSFFDVILTDPI---FPCGAVLAKYLQIPAV--FILRSLSCGIEYEATQCPNPS--SYI 193

  Fly   183 PNESTFATTPMSFFKRAENLVKHVILKYLTIRFNYKFNRIYNEIFTDKDMPTLSEMKKNISMVFV 247
            ||..|..:..|.|.:|.:|::.:::|||:.......:..:.:|:           :::.:|:|.|
Mouse   194 PNLLTRLSDHMDFLQRVQNMLYYLVLKYICRLSITPYESLASEL-----------LQREVSLVEV 247

  Fly   248 GSH---------LISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENSSQ-GAIFLSFGSN 302
            .||         .:.|.| ||::|.::.:|||....: .||.|:.|.::..|.: |.:..|.||.
Mouse   248 LSHASVWLFRGDFVLDYP-RPIMPNMVFIGGINCVTK-KPLSQEFEAYVNASGEHGIVVFSLGSM 310

  Fly   303 IKSYMVKP--EIVGIMFKVLSGLKQNVIWKWEDLENTPGN-ASNIFYKDWLPQDDILAHPNTKLF 364
            :.....|.  ||.    :.|..:.|.|:|::..  ..|.| |.|.....||||:|:|.||.|:.|
Mouse   311 VSEIPEKKAMEIA----EALGRIPQTVLWRYTG--TRPSNLAKNTILVKWLPQNDLLGHPKTRAF 369

  Fly   365 VTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVLEND 429
            :||:|...|.|...:|||||.:|:|||...||..|...|.||:|::..:|.|....|:..|:.|.
Mouse   370 ITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNK 434

  Fly   430 KYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVH-MGFVELHNLDIYALVLAI 493
            .|.:.:.:.|:|::|||:.|....:|||:||:||.|||:|: ||.| :.:.:.|:||:...:|||
Mouse   435 SYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAI 498

  Fly   494 LIFLVFLTRLTVKFLFSKLL-GKAKVPARKKKQ 525
            ::.:||:......:...|.. ||.:|....|.:
Mouse   499 VLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.2	Glycosyltransferase_GTB-type	39..517	CDD:471961	148/512 (29%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	151/529 (29%)