DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C1 and ugt-19

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_500912.2	Gene:	ugt-19 / 187129	WormBaseID:	WBGene00019515	Length:	532	Species:	Caenorhabditis elegans

Alignment Length:	527	Identity:	128/527 - (24%)
Similarity:	229/527 - (43%)	Gaps:	76/527 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STAKALAEAGHNVTVV------SMMQPKVMHKDIHLI-----VVPVTKEQERTLEN--------- 46
            :.|..|.:||||||||      |:.......|:|..:     |....|.:.:.|.|
Worm    39 AAADILTDAGHNVTVVMPVFDDSIKTSLKSTKNIIFVNSSDDVAAFAKARTKMLNNLWTMDNTNP 103

  Fly    47 -QMASMAGSKNN--------IITTMYLL----LNGLDVMVTSQADLLKDPRFQRVFETKFDLMIL 98
             .|.:..|..:|        ::|...|:    ....|:.||...||...|.|:.: ..:..:.||
Worm   104 FTMLTRVGMMSNTFSSQCKKVLTNTELIETMKAENYDLAVTEPFDLCAYPFFEAI-NIRAHVGIL 167

  Fly    99 GSFFNDFQLGVAGKLKVPVIVDWMIPSNTMIDEFVANPSEVSYVPNESTFATTPMSFFKRAENLV 163
            .|...|.                       :.:.:..|:..||.|...:..:..|:.::|..|::
Worm   168 SSSRLDH-----------------------VSDVIGQPAAPSYNPGLMSTNSDRMTMWQRFVNVI 209

  Fly   164 KHVILKYLTIRFNYKFNR---IYNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAII 225
            ::....|.   |:|..:|   :..||  :....:..|:....|.:......:.|.| .|....||
Worm   210 QYACGSYF---FSYIGDREAEVVKEI--NPKWRSWREVVPEASFIMTNQIPLLDFP-APTFDKII 268

  Fly   226 EVGGIQVKEQPDPLPQDIEQFME--NSSQGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNV- 287
            .:||:.||.....|..: |::.:  :..:..:|:|||||.:|..:..|......:|:..:....
Worm   269 PIGGLSVKTDKKSLKLE-EKWSKILDIRKKNVFISFGSNARSVDMPLEYKNTFLQVIKSMPDTTF 332

  Fly   288 IWKWEDLEN--TPGNASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFG 350
            |||:|||.:  |.| ..|::..|||||:::||.....:||||.|.||:||....|.|.|.:|:|.
Worm   333 IWKYEDLNDKFTEG-IENVYLGDWLPQNELLADKRLNVFVTHGGLGSVTELSMMGTPAVMIPLFA 396

  Fly   351 DHPLNAALMVNSGYGVSLDLQTITEDT--FREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSV 413
            |...|..::...| ||::..:|...|.  .:..|.|||.|.:|.::..:.:.:.|::|..|:::.
Worm   397 DQSRNGQMLKRHG-GVAVLKKTDLSDAKLVQSTIEEVLNNPEYRKSAERVAEMLRNQPTNPKETF 460

  Fly   414 LFWVDYVLRHHGAPNLQSPAVHMGFVELHNLDIYALVLAILIFLVFLTRLTVKFLFSKLLGKAKV 478
            |.:|::..|....|::.:....:.||:...|||.:::..|.:..::::...::....|..|....
Worm   461 LKYVEFTARFGKLPSMDNYGRQLTFVQYFFLDIISIISLITVVFLYISYKVIRCTIKKCFGSRSS 525

  Fly   479 PARKKKQ 485
            ..:.||:
Worm   526 EEKSKKE 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	126/517 (24%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	117/469 (25%)
ugt-19	NP_500912.2	egt	1..472	CDD:223071	117/465 (25%)
ugt-19	NP_500912.2	UDPGT	32..521	CDD:278624	125/514 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810