DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C1 and ugt-36

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_504820.2	Gene:	ugt-36 / 184266	WormBaseID:	WBGene00017315	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	512	Identity:	121/512 - (23%)
Similarity:	221/512 - (43%)	Gaps:	77/512 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 AKALAEAGHNVTVVSMMQPKVMHKDIHL-IVVPVTKEQERTLENQMASMAGS------------K 55
            |..|..||||||   ...|.::.|...: .|..:|...:....:::..: ||            :
Worm    44 ADTLTYAGHNVT---FFTPTIVRKFSKIQYVKSITHVLQLDPSDRLVKL-GSMFEEKDVSKFWYR 104

  Fly    56 NNIITTMYLLLNGLDVMVTSQADLLKDPRFQRVF----ETKFDLMILGSFFNDFQLGVAGKLKVP 116
            ::.::.|..:::..:.|...||.::.  |...|.    |..||:||...|.....|
Worm   105 DSSLSEMLPMIDTFNNMFVEQAAVIS--RNLHVLDDLKEMNFDVMIFEHFVEPAYL--------- 158

  Fly   117 VIVDWM-----IPSNTMIDEF-----VANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYL 171
             ::|::     ||:.::..::     :..|..:|.||..::..:..||..:|..|.:..:|...|
Worm   159 -VLDYLEIQKFIPATSLAFDYNMVKSIGEPLMLSTVPLPTSEYSDRMSLPQRLINAINPLIFDNL 222

  Fly   172 TIRFNYK-FNRIYNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQ 235
            ..:..|: :...|..|.|....|.       .|.||..|:...|.| |..:...::||||.|
Worm   223 IPKNKYRSYRPPYAPINTKSIEPF-------CSAVFTNSNPYIDYP-RATLEKNVQVGGISV--- 276

  Fly   236 PDPLPQDIEQFME-----------NSSQGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNV-- 287
                  ||::...           |.....:.:||||.:.|..: |....|....:.|...:|
Worm   277 ------DIDKLKSQKVSNEWDAVLNLRPKTVLVSFGSIMLSKDM-PINNKITIATVLGKFPDVTF 334

  Fly   288 IWKWEDLENTPGNAS-NIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGD 351
            |||:|..:.:..|.: ||.:.:|:||..:||.|....|.||||.||:.|..|.|.|.:..|||.|
Worm   335 IWKYETNDTSFANGTENIHFSNWVPQTALLADPRLSAFFTHAGLGSVNEVSYLGKPTIMCPIFAD 399

  Fly   352 HPLNAALMVNSGYGVSLDLQTITE-DTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLF 415
            ...||.::......:.:....::. |...||::::|.::.|..|..|.:....::|:.|::.::.
Worm   400 QMRNAKMLARHNGSIEISKYDLSNGDKIEEALSKILFDESYKTAAEKLAHQLANQPVKPKELLVR 464

  Fly   416 WVDYVLRHHGAPNLQSPAVHMGFVELHNLDIYALVLAILIFLVFLTRLTVKFLFSKL 472
            ..::..:....|:|...:..|.|::...:|:.|::|:.:|..:|:.....|.::|||
Worm   465 HAEFAAQFGHLPSLDPHSRQMSFIQYFLIDLTAIILSTVILFLFVLFKLGKLMYSKL 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	121/512 (24%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	109/469 (23%)
ugt-36	NP_504820.2	Glycosyltransferase_GTB_type	6..507	CDD:299143	116/496 (23%)
ugt-36	NP_504820.2	YjiC	25..455	CDD:224732	106/444 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810