DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C1 and ugt-65

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_502373.3	Gene:	ugt-65 / 184205	WormBaseID:	WBGene00008583	Length:	509	Species:	Caenorhabditis elegans

Alignment Length:	507	Identity:	119/507 - (23%)
Similarity:	201/507 - (39%)	Gaps:	91/507 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTAKALAEAGHNVTV--VSMMQPKVMHKDIHLIVVPVTKEQERTLENQMASMAGSKNNIITT-- 61
            |..|:.|.:.||:|::  :|..:.|:..|.:.::...|    :.:..:..|...|..:.|..:
Worm    42 MPLAERLFDDGHDVSMYTISANRLKIPSKKVKILESLV----KGSSTDDAAPDTGGVSRIFWSYE 102

  Fly    62 -------------MYLLLNGLDVMVTSQADLLKDPRFQRVFETKFDLMILGSFFNDFQLGVAGKL 113
                         :|.|..|            :|.:...|..|.:||.::...:...|..:|.||
Worm   103 MTPYVGAWCYEIGLYYLEEG------------RDEQLDEVLATPYDLAVVDETYTSLQGSIALKL 155

  Fly   114 K-------VPVIVDWMIPSNTMIDEFVANP----------SEVSYVPNESTFATTPMSFFK---- 157
            |       :......::|..:.:..:..||          ||| |..|...|.|.....|:
Worm   156 KEDHSTKIITFATTELMPVASNMRGYARNPVTVPNTFLLSSEV-YEGNRFAFLTRTRRIFEYFID 219

  Fly   158 -----RAENLVKHVILKYLTIRFNYKFNRIYNEIFTDKDMP-TLSEMK-KNISMVFVGSHLISDG 215
                 ...:|......|.|.:....|.....|.|.|..|.| |.|.:: :...::.||.|..|..
Worm   220 QIYSGPVASLYSEASGKLLGLTSATKSKTFQNSILTVNDFPDTFSFVQPRGNDLIRVGEHCYSSA 284

  Fly   216 PIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENS-SQGAIFLSFGSNIKSYMVKPEIVGIMFKV 279
                                  .||.:...|:|:| |:|.|:::.||.:.........|....:.
Worm   285 ----------------------NLPSEFRDFVEDSMSKGTIYVAMGSYLNLEDGPKGTVEAFIEA 327

  Fly   280 LSGLKQ-NVIWKWEDLENTPGNASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPM 343
            |:..|. .|||..:.  |..|...::...:|.||.::|||..|..|:||.|..|..|....||||
Worm   328 LNYFKDYRVIWSHKG--NVTGAKCHVKSVNWAPQKELLAHEKTVAFITHGGLKSAKEGVCSGVPM 390

  Fly   344 VALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLT 408
            :.||.:||.|.||...|.:|...:|..:.||....::.:.::|.:..|...|.|..:.|.|.|::
Worm   391 LFLPFYGDQPRNAHRFVTNGIAEALYKKAITSLDIQQKLEKLLVDPSYKNNVMKVLSYYLDAPIS 455

  Fly   409 PRQSVLFWVDYVLRHHGA--PNLQSPAVHMGFVELHNLDIYALVLAILIFLV 458
            ......|.:..|||...:  ...:..::.|..::..||||: ||:.:::|:|
Worm   456 SLDLGAFHISQVLRRTESQYSKFKRRSIFMNHLQYLNLDIF-LVILVILFIV 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	119/507 (23%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	108/475 (23%)
ugt-65	NP_502373.3	egt	<300..505	CDD:223071	59/207 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010