DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C1 and ugt-43

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001255487.1	Gene:	ugt-43 / 184052	WormBaseID:	WBGene00008485	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	514	Identity:	128/514 - (24%)
Similarity:	223/514 - (43%)	Gaps:	91/514 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STAKALAEAGHNVTVVSMM------------QPKVMHK---DIHLIVVPVTKEQERTLENQMASM 51
            :|:..|.|.|:|||::..:            ..|:.|:   |||..|:       ||: .:|..|
Worm    46 TTSNILQEEGYNVTLLLPLIDITLNNTNIPIVKKIKHRINLDIHPGVM-------RTI-IKMGGM 102

  Fly    52 AGSKNNIITTMYLLLNGLDVMVTSQADL---LKDPRF------QRVFETKFDLMILGSFFNDFQL 107
            |..:..  .||...:.|.|.:....:||   :.|..|      .|:...|:::.:...||
Worm   103 ASRRQT--WTMGSGIYGFDGISHLLSDLYSNICDNIFHMPGLLDRLKAEKYEMGMSEPFF----- 160

  Fly   108 GVAGKLKVPVIVDWMIPSNTMIDEFVANPSEV---------------SYVPNESTFATTPMSFFK 157
                      :..:.:..:..||:.::..|.:               ||:|...:.::..|||.:
Worm   161 ----------VCGFALFDHLGIDKIISVDSHIGLEGPKIAHGFPVTSSYLPAAFSESSDHMSFVE 215

  Fly   158 RAENLVKHVILKYLTIRFNYKFNRIYNEIFTD------KDMPTLSEMKKNISMVFVGSHLISDGP 216
            |..:|.:    .||    |.||.|:.:....|      |...|..|:.:..:.:|..|:.|.|.|
Worm   216 RTRSLYE----TYL----NRKFARLIHNKEIDAMKGVYKGKSTWEELMRLPAYMFTNSNPILDFP 272

  Fly   217 IRPLVPAIIEVGGIQV--KEQPDPLPQDIEQFMENSSQGAIFLSFGSNIKSYMVKPEIVGIMFKV 279
            . |.....||:|||..  |:..:.||:..:..: |.....:.:|||||.||..: |:.:.....:
Worm   273 Y-PRPSKFIEIGGIAADEKKHDEVLPESYDHIL-NLRNRTVLISFGSNAKSIFM-PDHMRRSLII 334

  Fly   280 LSGLKQNV--IWKWED-----LENTPGNASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQ 337
            ..|:..::  |||:|:     ::.......||...||:||..:||.|...|||||.|..|..|..
Worm   335 ALGMMPDITFIWKYENSSIDIVKEFDPTIKNIVQVDWMPQQALLADPRLDLFVTHGGMASTNEIA 399

  Fly   338 YHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTIT-EDTFREAINEVLENDKYTQAVRKFSAL 401
            :.|.|.|.:|:|||...|:.::...|..:.|..:.:. .:...|.|..||.:..|.:..::.:.|
Worm   400 FSGKPAVMVPVFGDQTRNSRMLERHGGVLMLRKENLEYPEIVIETILSVLNDPSYAERAQQLATL 464

  Fly   402 YRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGFVELHNLDIYALVLAILIFLVFL 460
            .|:.|.:|:|..|.:.::|.|......:.|.::::.|:..:.||:.|.:|.:..|..||
Worm   465 LRNHPESPKQVFLKYFNFVARFGKPTGIDSNSINVDFIAYYYLDLIAFLLIVAYFAKFL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	128/514 (25%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	119/481 (25%)
ugt-43	NP_001255487.1	Glycosyltransferase_GTB_type	<215..517	CDD:299143	86/312 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810