DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C1 and ugt-51

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_504388.2	Gene:	ugt-51 / 178905	WormBaseID:	WBGene00015369	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	517	Identity:	122/517 - (23%)
Similarity:	216/517 - (41%)	Gaps:	96/517 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STAKALAEAGHNVTVV----------------------SMMQPKVMHKDIHLI------VVPVTK 38
            |...:|.|.||.|.:|                      ........||..||.      ..|:..
Worm    41 SLIDSLKEKGHTVDLVIARINDLAKGNENSKADRFYTLGFKNGSSWHKLNHLTSPFENNPFPIDG 105

  Fly    39 EQERTL-ENQMASMAGSKNNIITTMYLLLNGLDVMVTSQADLLKDPRF-QRVFETKFDLMILGSF 101
            .::.|| .||:..:|                           |.|.:. |.:.|..:|:.:: |.
Worm   106 FRQYTLIGNQLCEIA---------------------------LHDEKLHQFLSEKSYDVGVV-SV 142

  Fly   102 FNDFQLGVAGKLKVPVIVDW-MIPSNTMIDEFVANPSEVS-YVPNESTFATTPMSFFKRAENLV- 163
            |:...:|:..|..|..|..: .:|..::....:..|:..| .||...||....:|  .:..||:
Worm   143 FDYCGIGILNKAGVSSITTFNAVPLMSIQTVTIGLPNIASQVVPLFYTFDLATLS--GKLWNLIT 205

  Fly   164 -KHVILKYL-TIRFNYK--FNRIYNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAI 224
             .|:....: |:|...:  |.::|...|      :::|:...:.:.||.|:.|.:.|:  |:...
Worm   206 WAHINFHQIPTLRKEQELLFQKVYGPSF------SINEVIDKVDLSFVNSNEIMETPM--LINHR 262

  Fly   225 IE-VGGIQVKEQPDPLPQDIEQFMENSSQGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQ-NV 287
            |: :|||.:| .|.|:...::..:..||.|.|..|||:.|...:.....|....||.....: ..
Worm   263 IQYIGGINLK-TPKPVDHHLDNLLSKSSNGTIIFSFGTQIPGAVYPRYAVRNFVKVFKKYPEYTF 326

  Fly   288 IWKWEDLENTPG------NASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVAL 346
            :||:   ...||      :|.|:...|||||.|:|..|....|::|.|..|..|:.|.|.|::|:
Worm   327 LWKY---NVQPGEEKLFEDAENVILLDWLPQTDLLYDPRVIGFISHVGLNSFNEASYAGKPIIAI 388

  Fly   347 PIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQ 411
            |:|.|.|.||...|..|....|:...::|::....:..:|.:..||::.||...:..::|..|:.
Worm   389 PLFADQPHNARNGVARGTTYLLNKSKLSEESIENGLRAILFDKSYTESARKLQKMLVEKPTKPKD 453

  Fly   412 SVLFWVDYVLRHHGAPNLQS-PAVHMGFVELHNLDIYALVLAILIFLVFLTRLTVKFLFSKL 472
            ..:.|::|...:.|...:.: |...||.:|.:.:|       .::|:.| :.:|..::|.|:
Worm   454 RFVEWMEYAAVNPGLHKIFALPGAKMGNIEYYCVD-------TIVFIAF-SCVTFTYIFFKM 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	122/517 (24%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	111/472 (24%)
ugt-51	NP_504388.2	UDPGT	43..505	CDD:278624	119/511 (23%)
ugt-51	NP_504388.2	egt	<217..496	CDD:223071	79/298 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810