DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C1 and ugt5a4

DIOPT Version :9

Sequence 1:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001170969.2	Gene:	ugt5a4 / 100415798	ZFINID:	ZDB-GENE-100406-1	Length:	525	Species:	Danio rerio

Alignment Length:	533	Identity:	149/533 - (27%)
Similarity:	244/533 - (45%)	Gaps:	125/533 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LAEAGHNVTVVS------MMQPKVMHKDI-----------------HLIVVPVTKEQERTLENQM 48
            |...||::|||.      :.:...::..|                 ||:.:   :.|.::...:|
Zfish    45 LHSKGHSITVVRASNSWYIEEQSPLYTSITVENGEFDADFGEKFLPHLLKM---QRQGKSFWTEM 106

  Fly    49 ASMAGSKNNIIT-----------TMY---LLLNGL-----DVMVTSQADLLKDPRFQRVFETKFD 94
            | :|....:..|           ||:   .|:|.|     ||::|       ||.|
Zfish   107 A-LADETYSRFTEIHQEICKMTATMFENETLMNSLKDAAYDVVLT-------DPAF--------- 154

  Fly    95 LMILGSFFNDFQLGV--AGKLKVPVI--VDWMIPSNTMIDE--FVANPSEVSYVPNESTFATTPM 153
                |.       ||  |.:|.:|::  |.|     ||..|  ||..||.:||||......|..|
Zfish   155 ----GG-------GVLLAHRLGLPLVFNVRW-----TMYGEAHFVIAPSPLSYVPVSGLQLTDKM 203

  Fly   154 SFFKRAENLVKHVILKYLTIRFNYKFNRIYNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGPI- 217
            :|.:|..|::.::::.|...::   |...|.|:       |......|::..    .|:.|..:
Zfish   204 TFSQRVMNMMTYIMILYKNSKY---FGSPYQEL-------TQKYFGPNVNFF----SLLQDADLW 254

  Fly   218 -----------RPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENSSQ-GAIFLSFGSNIKSYM--V 268
                       ||.:|.::.:||.|.| ...|||.|:|:|:::|.: |.|.:|.|:.....:  :
Zfish   255 LMRNDFTFEFPRPTMPNVVYMGGFQCK-PAKPLPGDLEEFVQSSGEHGVIMMSLGAVFGQLLSEL 318

  Fly   269 KPEIVGIMFKVLSGLKQNVIWKWEDLENTPGN-ASNIFYKDWLPQDDILAHPNTKLFVTHAGKGS 332
            ..||..    ..:.|.|.|||::..  ..|.| .:|....:||||:|:|.||.|||||.|.|...
Zfish   319 NDEIAA----AFAQLPQKVIWRYTG--PRPANLGNNSLIVNWLPQNDLLGHPKTKLFVAHGGTNG 377

  Fly   333 ITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRK 397
            :.|:.|||||:|.||:..|.|.|.:.|...|....:|:.|:....|.||:.|||.|..|.:.:::
Zfish   378 LQEAIYHGVPIVGLPLAFDQPDNLSRMRAKGTAKIVDIATLDRAVFLEALKEVLHNPSYRENMQR 442

  Fly   398 FSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGFVELHNLD-IYALVLAILIFLVFLT 461
            .|.|:.|:|:.|....:||:::|:|:.|||:|::.:..|.::|..::| |..|::.:|:|.:...
Zfish   443 LSKLHHDQPMKPLDRAIFWIEFVMRNKGAPHLRTQSFRMSWIEYQSIDVILTLMVMVLVFALVTA 507

  Fly   462 RLTVKF---LFSK 471
            .:|..|   ||.|
Zfish   508 YMTKYFCLRLFRK 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	149/533 (28%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	137/489 (28%)
ugt5a4	NP_001170969.2	UDPGT	23..525	CDD:278624	149/533 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000