Protein Alignment Gclc and gclc

DIOPT Version :10

• Sequence 1: NP_525005.2
• Gene: Gclc / 53581
• FlyBaseID: FBgn0040319
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_954971.2
• Gene: gclc / 326857
• ZFINID: ZDB-GENE-030131-5056
• Length: 631
• Species: Danio rerio
• Alignment Length: 702
• Identity: 374/702 - (53%)
• Similarity: 474/702 - (67%)
• Gaps: 91/702 - (12%)

  Fly     1 MGLLSEGSPLSWEETKALADHVREHGVNQFINLYHRLKDRQGDILKWGDEVEYIIVKFDDEQKVA 65
            |||||:||||:|||||..|||||:||:.||:|:|:::||||.|:|||||||||::|..||:.:..
Zfish     1 MGLLSQGSPLNWEETKKHADHVRKHGILQFLNIYNKVKDRQKDVLKWGDEVEYMLVNMDDQNEKV 65

  Fly    66 RVALRAQDLLAQLNEK-ELADPNGVKSLWRPEYGAYMIEGTPGKPFGGLMAHFNLVEANMRYRRE 129
            |:.|..:::|..|.|| |..:||. .:|||||||:||||||||:|:||.|:.||.||.||..||.
Zfish    66 RLVLNGKEVLEILQEKGENINPNH-PTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEDNMGKRRR 129

  Fly   130 EVTELLAKDECVMSITNFPRLGAPNFTYPLAQPRPEDPLSSARSLYFPDEAIFPGHPRFKTLTRN 194
            |.:.:|.|:|.::::|.|||||.|.||.|..:|.|.:. ..::||:|||||| ..||||.|||||
Zfish   130 EASSVLKKNETLLTVTAFPRLGCPGFTLPEYKPTPVEK-GVSKSLFFPDEAI-NRHPRFSTLTRN 192

  Fly   195 IRKRRGEKVSIKLKVFKDTKTKLPV---------EGAPPGEPDVVLLDAMGFGMGCCCLQLTFQA 250
            ||.||||||.|.:.:|||..|..|.         |.|...:||.:.:||||||||.||||:||||
Zfish   193 IRHRRGEKVVINVPIFKDINTPSPFMEVFPEDDGEAARGAKPDHIYMDAMGFGMGNCCLQVTFQA 257

  Fly   251 CNITEARRLYDQLAPLCPIMLALTAASPIYRGYLTESDCRWNVISSSVDCRTEEERGLAPLDQQK 315
            |:|:|||.||||||..|||::||:||||.|||::::.||||.|||:|||.||.|||||..|...|
Zfish   258 CSISEARYLYDQLATFCPIVMALSAASPFYRGFVSDIDCRWGVISASVDDRTREERGLESLKNNK 322

  Fly   316 FRIAKSRYDSIDSYLSPEGAKYNDVPLTYDEKVYQRLVEGGIDHLLAQHVAHLFIRDTVSLFSEK 380
            |||.||||||||||||..|.||||:.||.||.:.::|::.|||.|||||:|||||||.:|||.||
Zfish   323 FRIHKSRYDSIDSYLSCCGEKYNDIELTIDEDINKQLLDAGIDKLLAQHIAHLFIRDPLSLFQEK 387

  Fly   381 VHQNDNEDTDHFENIQSTNWQTMRFKPPPPNSSIGWRVEFRPCEAQISDFENAAIVCFVVLLTRV 445
            :|.:|..::|||||||||||||||||||||||.|||||||||.|.|::||||:|.|.|:||||||
Zfish   388 IHLDDENESDHFENIQSTNWQTMRFKPPPPNSEIGWRVEFRPMEVQLTDFENSAYVVFIVLLTRV 452

  Fly   446 ILSYQLNFLTPISKVDENMQTAQKRDACRKEKFWFR----KSSKTTEQRAAKAQAQAQAQAKAQA 506
            ||||:|:||.|:|||||||:.||||:|.::..|:||    |.......|...||
Zfish   453 ILSYKLDFLIPLSKVDENMKVAQKRNAVQEGMFYFRKDVFKGCTPVLDRPGAAQ----------- 506

  Fly   507 QTNGKATLNGNGLANGNGNGSENSDQEEQQPLTNGSAKMNGHGSGTTNGTNGSSNGSSNGTDSDH 571
                      |||                                                   .
Zfish   507 ----------NGL---------------------------------------------------E 510

  Fly   572 TDTDDEENELFQLLSINEIFNGKPNVFPGLVPLIRSYLQSMEVDTDTHCTIEQYLRFIQKRAAGE 636
            |:|:|.|.  |.|:||:.|.|||..||.||:|::.|||::||||.||.|||..||:.|:|||:|:
Zfish   511 TETNDGEE--FILMSIDTIINGKEGVFHGLIPMLNSYLENMEVDVDTRCTILNYLKLIKKRASGD 573

  Fly   637 LITTATWMREQVLSHPDYKQDSVVSERINYDLLKRIQGIQEGKQVEPALLGQ 688
            |:|.|.||||.|..||.||||||::::||||||.:...|.:|::..|.|:|:
Zfish   574 LMTMAKWMREFVAKHPQYKQDSVITDKINYDLLHKCDRIAKGEEKCPELIGE 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclc	NP_525005.2	GCS	232..675	CDD:460796	240/446 (54%)
gclc	NP_954971.2	GCS	237..612	CDD:460796	240/448 (54%)