Protein Alignment Gclc and Gclc

DIOPT Version :9

• Sequence 1: NP_001285001.1
• Gene: Gclc / 53581
• FlyBaseID: FBgn0040319
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_036947.1
• Gene: Gclc / 25283
• RGDID: 619868
• Length: 637
• Species: Rattus norvegicus
• Alignment Length: 699
• Identity: 373/699 - (53%)
• Similarity: 473/699 - (67%)
• Gaps: 85/699 - (12%)

  Fly     1 MGLLSEGSPLSWEETKALADHVREHGVNQFINLYHRLKDRQGDILKWGDEVEYIIVKFDDEQKVA 65
            |||||:|||||||||:..|||||.||:.||:::||.:|||..|:|||||||||::|.||.|.:..
  Rat     1 MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDHENRKV 65

  Fly    66 RVALRAQDLLAQLNEK-ELADPNGVKSLWRPEYGAYMIEGTPGKPFGGLMAHFNLVEANMRYRRE 129
            ::.|...|:|..|.|| |..:||. .:|||||||:||||||||:|:||.|:.||.||.|||.||:
  Rat    66 QLLLNGGDVLETLQEKGERTNPNH-PTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEDNMRKRRK 129

  Fly   130 EVTELLAKDECVMSITNFPRLGAPNFTYPLAQPRPEDPLSSARSLYFPDEAIFPGHPRFKTLTRN 194
            |.|.:|.:.:.:.:||:|||||.|.||.|..:|.||:. .:::||:|||||| ..||||.|||||
  Rat   130 EATSVLGEHQALCTITSFPRLGCPGFTLPEHRPNPEEG-GASKSLFFPDEAI-NKHPRFGTLTRN 192

  Fly   195 IRKRRGEKVSIKLKVFKDTKTKLP-VEGAPPGE-------PDVVLLDAMGFGMGCCCLQLTFQAC 251
            ||.||||||.|.:.:|||..|..| ||..|..|       ||.:.:||||||||.||||:|||||
  Rat   193 IRHRRGEKVVINVPIFKDKNTPSPFVETFPEDEEASKASKPDHIYMDAMGFGMGNCCLQVTFQAC 257

  Fly   252 NITEARRLYDQLAPLCPIMLALTAASPIYRGYLTESDCRWNVISSSVDCRTEEERGLAPLDQQKF 316
            :|:|||.||||||.:|||::||:||||.||||:::.||||.|||:|||.||.|||||.||...:|
  Rat   258 SISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVISASVDDRTREERGLEPLKNNRF 322

  Fly   317 RIAKSRYDSIDSYLSPEGAKYNDVPLTYDEKVYQRLVEGGIDHLLAQHVAHLFIRDTVSLFSEKV 381
            :|:||||||||||||..|.||||:.||.|.::|::|:|.|||||||||||||||||.::||.||:
  Rat   323 KISKSRYDSIDSYLSKCGEKYNDIDLTIDTEIYEQLLEEGIDHLLAQHVAHLFIRDPLTLFEEKI 387

  Fly   382 HQNDNEDTDHFENIQSTNWQTMRFKPPPPNSSIGWRVEFRPCEAQISDFENAAIVCFVVLLTRVI 446
            |.:|..::|||||||||||||||||||||||.|||||||||.|.|::||||:|.|.|||||||||
  Rat   388 HLDDANESDHFENIQSTNWQTMRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVI 452

  Fly   447 LSYQLNFLTPISKVDENMQTAQKRDACRKEKFWFRKSSKTTEQRAAKAQAQAQAQAKAQAQTNGK 511
            |||:|:||.|:|||||||:.||:|||..:..|:|||.
  Rat   453 LSYKLDFLIPLSKVDENMKVAQERDAVLQGMFYFRKD---------------------------- 489

  Fly   512 ATLNGNGLANGNGNGSENSDQEEQQPLTNGSAKMNGHGSGTTNGTNGSSNGSSNGTDSDHTDTDD 576
            ....||.:.:|......:|:...::
  Rat   490 ICKGGNAVVDGCSKAQTSSEPSAEE---------------------------------------- 514

  Fly   577 EENELFQLLSINEIFNGKPNVFPGLVPLIRSYLQSMEVDTDTHCTIEQYLRFIQKRAAGELITTA 641
                 :.|:||:.|.|||..|||||:|::.|||::||||.||.|:|..||:.|:|||:|||:|.|
  Rat   515 -----YTLMSIDTIINGKEGVFPGLIPILNSYLENMEVDVDTRCSILNYLKLIKKRASGELMTVA 574

  Fly   642 TWMREQVLSHPDYKQDSVVSERINYDLLKRIQGIQEGKQVEPALLGQDY 690
            .||||.:.:|||||||||:::.|||.|:.:...|.......|.|||..:
  Rat   575 RWMREFIANHPDYKQDSVITDEINYSLILKCNQIANELCECPELLGSGF 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclc	NP_001285001.1	GCS	232..675	CDD:281119	235/442 (53%)
Gclc	NP_036947.1	rpsA	<26..67	CDD:235775	22/40 (55%)
		GCS	236..608	CDD:397275	193/371 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348839
Domainoid	1	1.000	383	1.000	Domainoid score	I787
eggNOG	1	0.900	-	-		E1_KOG3754
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1148
Inparanoid	1	1.050	634	1.000	Inparanoid score	I802
OMA	1	1.010	-	-		QHG54052
OrthoDB	1	1.010	-	-		D126317at33208
OrthoFinder	1	1.000	-	-		FOG0005562
OrthoInspector	1	1.000	-	-		oto96647
orthoMCL	1	0.900	-	-		OOG6_102076
Panther	1	1.100	-	-	LDO	PTHR11164
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3981
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770