DRSC/TRiP Functional Genomics Resources

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Protein Alignment Jafrac1 and PRDX6

DIOPT Version :9

Sequence 1:NP_001285202.1 Gene:Jafrac1 / 53578 FlyBaseID:FBgn0040309 Length:194 Species:Drosophila melanogaster
Sequence 2:NP_004896.1 Gene:PRDX6 / 9588 HGNCID:16753 Length:224 Species:Homo sapiens


Alignment Length:191 Identity:61/191 - (31%)
Similarity:94/191 - (49%) Gaps:15/191 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 APAFAGTAVVNGVFKDIKLSDYKG-KYLVLFFYPLDFTFVCPTEIIAFSESAAEFRKINCEVIGC 71
            ||.|.....|.    .|:..|:.| .:.:||.:|.|||.||.||:...::.|.||.|.|.::|..
Human    11 APNFEANTTVG----RIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIAL 71

  Fly    72 STDSQFTHLAW---INTPRKQGGLGSMDIPLLADKSMKVARDYGVLD----EETGIPF--RGLFI 127
            |.||...||||   ||....:.....:..|::.|::.::|...|:||    :|.|:|.  |.:|:
Human    72 SIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLDPAEKDEKGMPVTARVVFV 136

  Fly   128 IDDKQNLRQITVNDLPVGRSVEETLRLVQAFQYTDKYGEVCPANWKPGQKTMVADPTKSKE 188
            ....:.|:...:.....||:.:|.||:|.:.|.|.:.....|.:||.|...||. ||..:|
Human   137 FGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDWKDGDSVMVL-PTIPEE 196

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Jafrac1NP_001285202.1 PRX_Typ2cys 4..175 CDD:239313 55/176 (31%)
PRDX6NP_004896.1 PRX_1cys 7..222 CDD:239314 61/191 (32%)
Required and sufficient for targeting to lysosomes and lamellar bodies. /evidence=ECO:0000250|UniProtKB:O35244 31..40 2/8 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0450
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100111
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.710

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