Protein Alignment Jafrac2 and PRDX6

DIOPT Version :9

• Sequence 1: NP_001261350.1
• Gene: Jafrac2 / 53577
• FlyBaseID: FBgn0040308
• Length: 242
• Species: Drosophila melanogaster
• Sequence 2: NP_004896.1
• Gene: PRDX6 / 9588
• HGNCID: 16753
• Length: 224
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 55/200 - (27%)
• Similarity: 90/200 - (45%)
• Gaps: 21/200 - (10%)

  Fly    56 APQFEGTAVVNKEIVKLSLSQYLG-KYVVLLFYPLDFTFVCPTEIIAFSDRIAEFKKIKTEVIGV 119
            ||.||    .|..:.::....:|| .:.:|..:|.|||.||.||:...:....||.|...::|.:
Human    11 APNFE----ANTTVGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIAL 71

  Fly   120 SVDSHFTHLAW---INTPRKEGGLGDVKIPLLSDLTHKISKDYGVYLESSGHALRGL-------F 174
            |:||...||||   ||....|.....:..|::.|...:::...|: |:.:....:|:       |
Human    72 SIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGM-LDPAEKDEKGMPVTARVVF 135

  Fly   175 IIDQTGVLRQITMNDLPVGRSVDETIRLVQAFQYTDTHGEVCPAGWRPGADTIVPNP----EEKT 235
            :......|:...:.....||:.||.:|:|.:.|.|.......|..|:.| |:::..|    ||..
Human   136 VFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDWKDG-DSVMVLPTIPEEEAK 199

  Fly   236 KYFAK 240
            |.|.|
Human   200 KLFPK 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jafrac2	NP_001261350.1	PRX_Typ2cys	52..223	CDD:239313	47/177 (27%)
PRDX6	NP_004896.1	PRX_1cys	7..222	CDD:239314	54/199 (27%)
		Required and sufficient for targeting to lysosomes and lamellar bodies. /evidence=ECO:0000250|UniProtKB:O35244	31..40		1/8 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.710