DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jafrac2 and prdx4

DIOPT Version :9

Sequence 1:	NP_001261350.1	Gene:	Jafrac2 / 53577	FlyBaseID:	FBgn0040308	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_001082894.1	Gene:	prdx4 / 570477	ZFINID:	ZDB-GENE-030131-1096	Length:	260	Species:	Danio rerio

Alignment Length:	242	Identity:	167/242 - (69%)
Similarity:	193/242 - (79%)	Gaps:	5/242 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SVLLLSAALV-GAAKPEDNESCYSFAGGSVYPDQ----PKGDHQLQYTKAVISKPAPQFEGTAVV 65
            ::||||.::| ..|..:..:.||::|||.|||.:    |..||.|..:||.||||||.:|||||:
Zfish    19 ALLLLSESVVCDGANGKREQECYNYAGGHVYPGEAFRVPVSDHSLHLSKAKISKPAPHWEGTAVI 83

  Fly    66 NKEIVKLSLSQYLGKYVVLLFYPLDFTFVCPTEIIAFSDRIAEFKKIKTEVIGVSVDSHFTHLAW 130
            |.|..:|.||.|.|||:|..||||||||||||||||||||:.||:.|..||:..||||.||||||
Zfish    84 NGEFKELKLSDYKGKYLVFFFYPLDFTFVCPTEIIAFSDRVHEFQAINAEVVACSVDSQFTHLAW 148

  Fly   131 INTPRKEGGLGDVKIPLLSDLTHKISKDYGVYLESSGHALRGLFIIDQTGVLRQITMNDLPVGRS 195
            ||||||:||||.:||||||||||:|||||||:||..||.||||||||..||||||||||||||||
Zfish   149 INTPRKQGGLGPMKIPLLSDLTHQISKDYGVFLEDQGHTLRGLFIIDGKGVLRQITMNDLPVGRS 213

  Fly   196 VDETIRLVQAFQYTDTHGEVCPAGWRPGADTIVPNPEEKTKYFAKNN 242
            ||||:||||||||||.|||||||||:||:|||:|:|..|.|||.|.|
Zfish   214 VDETLRLVQAFQYTDKHGEVCPAGWKPGSDTIIPDPAGKLKYFDKLN 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jafrac2	NP_001261350.1	PRX_Typ2cys	52..223	CDD:239313	134/170 (79%)
prdx4	NP_001082894.1	PTZ00253	68..256	CDD:140280	144/187 (77%)
prdx4	NP_001082894.1	PRX_Typ2cys	70..241	CDD:239313	134/170 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596671
Domainoid	1	1.000	210	1.000	Domainoid score	I2775
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4672
Inparanoid	1	1.050	341	1.000	Inparanoid score	I2326
OMA	1	1.010	-	-		QHG54000
OrthoDB	1	1.010	-	-		D1326484at2759
OrthoFinder	1	1.000	-	-		FOG0000434
OrthoInspector	1	1.000	-	-		oto39537
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	1	1.100	-	-	LDO	PTHR10681
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9109
SonicParanoid	1	1.000	-	-		X272
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800