DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jafrac2 and PRDX4

DIOPT Version :9

Sequence 1:	NP_001261350.1	Gene:	Jafrac2 / 53577	FlyBaseID:	FBgn0040308	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_006397.1	Gene:	PRDX4 / 10549	HGNCID:	17169	Length:	271	Species:	Homo sapiens

Alignment Length:	247	Identity:	161/247 - (65%)
Similarity:	190/247 - (76%)	Gaps:	9/247 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LSVLLLSAALVGAAKPED-----NESCYSFAGGSVYPDQPK----GDHQLQYTKAVISKPAPQFE 60
            |.:.||.|..|...:.|:     .|.|:.:|||.|||.:..    .||.|..:||.||||||.:|
Human    25 LLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWE 89

  Fly    61 GTAVVNKEIVKLSLSQYLGKYVVLLFYPLDFTFVCPTEIIAFSDRIAEFKKIKTEVIGVSVDSHF 125
            ||||::.|..:|.|:.|.|||:|..|||||||||||||||||.||:.||:.|.|||:..||||.|
Human    90 GTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQF 154

  Fly   126 THLAWINTPRKEGGLGDVKIPLLSDLTHKISKDYGVYLESSGHALRGLFIIDQTGVLRQITMNDL 190
            ||||||||||::||||.::|||||||||:||||||||||.|||.||||||||..|:|||||:|||
Human   155 THLAWINTPRRQGGLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDL 219

  Fly   191 PVGRSVDETIRLVQAFQYTDTHGEVCPAGWRPGADTIVPNPEEKTKYFAKNN 242
            |||||||||:||||||||||.|||||||||:||::||:|:|..|.|||.|.|
Human   220 PVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jafrac2	NP_001261350.1	PRX_Typ2cys	52..223	CDD:239313	130/170 (76%)
PRDX4	NP_006397.1	PRX_Typ2cys	81..252	CDD:239313	130/170 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160322
Domainoid	1	1.000	207	1.000	Domainoid score	I2899
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4672
Inparanoid	1	1.050	331	1.000	Inparanoid score	I2447
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54000
OrthoDB	1	1.010	-	-		D1326484at2759
OrthoFinder	1	1.000	-	-		FOG0000434
OrthoInspector	1	1.000	-	-		oto89843
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	1	1.100	-	-	LDO	PTHR10681
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9109
SonicParanoid	1	1.000	-	-		X272
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800