DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ilk and YGL242C

DIOPT Version :9

Sequence 1:	NP_525001.2	Gene:	Ilk / 53573	FlyBaseID:	FBgn0028427	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_011272.1	Gene:	YGL242C / 852609	SGDID:	S000003211	Length:	181	Species:	Saccharomyces cerevisiae

Alignment Length:	173	Identity:	32/173 - (18%)
Similarity:	58/173 - (33%)	Gaps:	40/173 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EDIFHWCREGNSIQVRLWLDETEHD--------NNLGDDHGFSPLHWVAKEGHAKLVETLLQRGS 58
            |.:....|..|...:....|..::|        |...:..|.:.||...|.|..::::.:|.:..
Yeast    10 EQLLDAARRNNLDLLETVFDSLDNDPEKIAKLINESKEPLGNTALHLCCKYGSWEVLDKILDQDG 74

  Fly    59 RVNATNMGD---DIPLHLAAAHGHRDVVQMLIKERSDVNAVNEHGNTPLHYACFWGYDMICEDLL 120
            .:......|   |.|||:...:...:               .|||.            .|..:|:
Yeast    75 EIEIDPQNDVDGDTPLHVTVRYSQEE---------------PEHGT------------FIARNLI 112

  Fly   121 NAGAQVGIANKDGHTPLEKAKPSLAKRLQDLVEKSGREVKVIS 163
            ..||...:.|.:...|::.........|.||::  |.|:.:.|
Yeast   113 EVGADPRVRNYNNQKPVDLVHGDELDELIDLLQ--GAELAIDS 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANK	28..140	CDD:238125	20/114 (18%)
		ANK repeat	33..64	CDD:293786	6/30 (20%)
		Ank_2	38..130	CDD:289560	17/94 (18%)
		ANK repeat	66..97	CDD:293786	5/33 (15%)
		ANK repeat	99..130	CDD:293786	6/30 (20%)
		PK_ILK	196..446	CDD:270959
		STYKc	204..443	CDD:214568
YGL242C	NP_011272.1	Ank_2	12..122	CDD:403870	23/136 (17%)
		ANK repeat	12..47	CDD:293786	5/34 (15%)
		ANK repeat	49..83	CDD:293786	6/33 (18%)
		ANK repeat	85..122	CDD:293786	11/63 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000