DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ilk and AT1G67890

DIOPT Version :9

Sequence 1:	NP_525001.2	Gene:	Ilk / 53573	FlyBaseID:	FBgn0028427	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_564913.1	Gene:	AT1G67890 / 843117	AraportID:	AT1G67890	Length:	765	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	116/532 - (21%)
Similarity:	214/532 - (40%)	Gaps:	112/532 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 WCREGNSIQVRLWLDETEH-DNNLGDDHGFSPLHWVAKEGHAKLVETLLQRGSRVNA-TNMGDDI 69
            :||..|.:..||..|..|. .:.||.| ...|:.....   :|:.:...:.|::|.: ...||:.
plant   234 FCRGTNGVASRLGFDSKEAVVSKLGLD-SQQPIQAAIA---SKISDLASKVGNKVRSKMRAGDNN 294

  Fly    70 PLHLAAAHG--HR------DVVQMLIKERSDVN-AVNEHGN---TPLHYACFWGYDMICEDLLNA 122
            ..|....:|  |:      |......:|.::.| |....||   :|  :..|     :|.|..::
plant   295 ASHPEGGNGGSHQSDQGFFDAAFSDQREDAETNDASTPRGNLIQSP--FGVF-----LCNDDKSS 352

  Fly   123 GAQVGIAN--KDGHTPLEKAKPSLAKRLQDLVEKSG---------------------------RE 158
            ....|.:|  .|.::.:.|   .|..:.::.:.|.|                           .:
plant   353 SKASGESNDENDRNSVVPK---KLTSKTEEWMVKKGLSWPWKGNEREGLERRNAHSVWPWVHNEQ 414

  Fly   159 VKVISFKEQSWQGLKTRSRDATLSR-FKGISMGDLDLHTKLSVTPSGET---------------- 206
            .|..:....|:..:|:.|..:..:: ....:||.:::::..|.:..|.|
plant   415 QKEEAHHSNSYNSVKSESLASESNKPANNENMGSVNVNSASSASSCGSTSSSVMNKVDMDSDCLD 479

  Fly   207 ----------------------WRGRWQKNDVVAKILAVRQCTPRISRDFNEEFPKLRIFSHPNI 249
                                  :.|.|..:||..|:.:.::.:..|...|.:|...::...|||:
plant   480 YEILWEDLTIGEQIGQGSCGTVYHGLWFGSDVAVKVFSKQEYSEEIITSFKQEVSLMKRLRHPNV 544

  Fly   250 LPIIGACNSPPNLVTISQFMPRSSLFSLLHGATGVVVDTSQAVSFALDVARGMAFLHSLERIIPT 314
            |..:||..||..|..:::|:||.|||.||. .....:|..:.:..|.|:||||.:||.....|..
plant   545 LLFMGAVASPQRLCIVTEFLPRGSLFRLLQ-RNKSKLDLRRRIHMASDIARGMNYLHHCSPPIIH 608

  Fly   315 YHLNSHHVMIDDDLTARINMGDAKFSFQE-KGRIY-------QPAWMSPETLQRKQADRNWEACD 371
            ..|.|.::::|.:.|.::    |.|.... |...|       .|.||:||.|:.:.||   |..|
plant   609 RDLKSSNLLVDRNWTVKV----ADFGLSRIKHETYLTTNGRGTPQWMAPEVLRNEAAD---EKSD 666

  Fly   372 MWSFAILIWELTTREVPFAEWSPMECGMKIALEGLRVKIPPGTSTHMAKLISICMNEDPGKRPKF 436
            ::||.:::|||.|.::|:...:.|:....:.....|:::|.........|:..|.:.:|..||.|
plant   667 VYSFGVVLWELVTEKIPWENLNAMQVIGAVGFMNQRLEVPKDVDPQWIALMESCWHSEPQCRPSF 731

  Fly   437 DMVVPILEKMRR 448
            ..::..|.:::|
plant   732 QELMDKLRELQR 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANK	28..140	CDD:238125	25/126 (20%)
		ANK repeat	33..64	CDD:293786	4/31 (13%)
		Ank_2	38..130	CDD:289560	19/104 (18%)
		ANK repeat	66..97	CDD:293786	9/39 (23%)
		ANK repeat	99..130	CDD:293786	7/33 (21%)
		PK_ILK	196..446	CDD:270959	73/295 (25%)
		STYKc	204..443	CDD:214568	71/284 (25%)
AT1G67890	NP_564913.1	PAS	101..211	CDD:395786
AT1G67890	NP_564913.1	STKc_MAP3K-like	493..738	CDD:270901	69/252 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910