DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ilk and AT5G50180

DIOPT Version :9

Sequence 1:	NP_525001.2	Gene:	Ilk / 53573	FlyBaseID:	FBgn0028427	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_199829.1	Gene:	AT5G50180 / 835083	AraportID:	AT5G50180	Length:	346	Species:	Arabidopsis thaliana

Alignment Length:	306	Identity:	86/306 - (28%)
Similarity:	129/306 - (42%)	Gaps:	63/306 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 EQSWQGLKTRSRDATLSRFKGISMGDLDLHTKLSVTPSGETWRGRWQKNDVVAKILAVRQCTP-- 228
            |..||      .|..| .|.|..:|: ..|.|:        :.|:: ||..||..:..|..||
plant    10 EPKWQ------IDPQL-LFVGPKIGE-GAHAKV--------YEGKY-KNQTVAIKIVHRGETPEE 57

  Fly   229 ---RISRDFNEEFPKLRIFSHPNILPIIGACNSPPNLVTISQFMPRSSLFSLLHGATGVVVDTSQ 290
               |.|| |..|...|....|.|::..||||..|. :|.:::.:...:|...|.......::|..
plant    58 IAKRDSR-FLREVEMLSRVQHKNLVKFIGACKEPV-MVIVTELLQGGTLRKYLLNLRPACLETRV 120

  Fly   291 AVSFALDVARGMAFLHSLERIIPTYHLNSHHVMIDDD-------LTA---RINMGDAKFSFQEKG 345
            |:.||||:||||..|||             |.:|..|       |||   .:.:.|...:.:|..
plant   121 AIGFALDIARGMECLHS-------------HGIIHRDLKPENLLLTADHKTVKLADFGLAREESL 172

  Fly   346 RIYQPA------WMSPE-----TLQRKQADRNWEACDMWSFAILIWELTTREVPFAEWSPMECGM 399
            .....|      ||:||     ||:..:........|.:||||::|||...::||...|.::...
plant   173 TEMMTAETGTYRWMAPELYSTVTLRLGEKKHYNHKVDAYSFAIVLWELLHNKLPFEGMSNLQAAY 237

  Fly   400 KIALEGLRVKIPPGTS--THMAKLISICMNEDPGKRPKFDMVVPIL 443
            ..|.:.:|   |...|  ..:..:::.|.||||..||.|..::.:|
plant   238 AAAFKNVR---PSAESLPEELGDIVTSCWNEDPNARPNFTHIIELL 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANK	28..140	CDD:238125
		ANK repeat	33..64	CDD:293786
		Ank_2	38..130	CDD:289560
		ANK repeat	66..97	CDD:293786
		ANK repeat	99..130	CDD:293786
		PK_ILK	196..446	CDD:270959	77/276 (28%)
		STYKc	204..443	CDD:214568	75/266 (28%)
AT5G50180	NP_199829.1	STKc_MAP3K-like	26..280	CDD:270901	78/281 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910