DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ilk and STY46

DIOPT Version :9

Sequence 1:	NP_525001.2	Gene:	Ilk / 53573	FlyBaseID:	FBgn0028427	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_568041.1	Gene:	STY46 / 830003	AraportID:	AT4G38470	Length:	575	Species:	Arabidopsis thaliana

Alignment Length:	429	Identity:	106/429 - (24%)
Similarity:	191/429 - (44%)	Gaps:	70/429 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 LHLAAAHGHRDVVQMLIKERS---DVNAVNE-HGNT----PLHYACFWGYD----------MICE 117
            :|...|.|....::.|....|   |.:|.|. |.|:    |||...|...|          ::.|
plant   135 IHPPPAFGSSPNLEALALAASLSQDEDADNSVHNNSLYSRPLHEITFSTEDKPKLLFQLTALLAE 199

  Fly   118 DLLNAGAQVGIANKDGHT---------PLEKAKPSLAKRLQDLVEKSGREVKVISFKEQSW---- 169
            ..||.......:..||::         |.|:     .:||:..:||   |...|..:.|||
plant   200 LGLNIQEAHAFSTTDGYSLDVFVVDGWPYEE-----TERLRISLEK---EAAKIELQSQSWPMQQ 256

  Fly   170 ----------QGLKTR---SRDATLSRFKGISMGDLDLHTKLSVTPSGETWRGRWQKNDVVAKIL 221
                      .|.:|.   ..|.|  ....|::..|....|::....|:.::|.:...:|..|:|
plant   257 SFSPEKENGQTGARTHVPIPNDGT--DVWEINLKHLKFGHKIASGSYGDLYKGTYCSQEVAIKVL 319

  Fly   222 AVRQCTPRISRDFNEEFPKLRIFSHPNILPIIGACNSPPNLVTISQFMPRSSLFSLLHGATGVVV 286
            ...:....:.::|.:|...:|...|.|::..||||..||:|..:::|||..|::..||...| |.
plant   320 KPERLDSDLEKEFAQEVFIMRKVRHKNVVQFIGACTKPPHLCIVTEFMPGGSVYDYLHKQKG-VF 383

  Fly   287 DTSQAVSFALDVARGMAFLHSLERIIPTYHLNSHHVMIDDDLTARI-NMGDAKFSFQ------EK 344
            ........|:|:.:||::||  :..|....|.:.::::|::...:: :.|.|:...|      |.
plant   384 KLPTLFKVAIDICKGMSYLH--QNNIIHRDLKAANLLMDENEVVKVADFGVARVKAQTGVMTAET 446

  Fly   345 GRIYQPAWMSPETLQRKQADRNWEACDMWSFAILIWELTTREVPFAEWSPMECGMKIALEGLRVK 409
            | .|:  ||:||.::.|..|..   .|::|:.|::|||.|.::|:...:|::..:.:..:|||..
plant   447 G-TYR--WMAPEVIEHKPYDHK---ADVFSYGIVLWELLTGKLPYEYMTPLQAAVGVVQKGLRPT 505

  Fly   410 IPPGTSTHMAKLISICMNEDPGKRPKFDMVVPILEKMRR 448
            ||..|...:|:|:......|..:||.|..::..|:::.:
plant   506 IPKNTHPKLAELLERLWEHDSTQRPDFSEIIEQLQEIAK 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANK	28..140	CDD:238125	22/95 (23%)
		ANK repeat	33..64	CDD:293786
		Ank_2	38..130	CDD:289560	18/76 (24%)
		ANK repeat	66..97	CDD:293786	7/28 (25%)
		ANK repeat	99..130	CDD:293786	10/44 (23%)
		PK_ILK	196..446	CDD:270959	69/256 (27%)
		STYKc	204..443	CDD:214568	67/245 (27%)
STY46	NP_568041.1	ACT	176..241	CDD:415594	15/72 (21%)
STY46	NP_568041.1	STKc_MAP3K-like	296..539	CDD:270901	67/251 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	126	1.000	Inparanoid score	I1926
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960