DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ilk and STY17

DIOPT Version :9

Sequence 1:	NP_525001.2	Gene:	Ilk / 53573	FlyBaseID:	FBgn0028427	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_195303.2	Gene:	STY17 / 829731	AraportID:	AT4G35780	Length:	570	Species:	Arabidopsis thaliana

Alignment Length:	425	Identity:	108/425 - (25%)
Similarity:	187/425 - (44%)	Gaps:	80/425 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 AAAHGHRDVVQMLIKERSDVNAVNEH--GNTPLHYACFWGYD--MICEDLLNAGAQVGIANKDGH 134
            |....::|..|      .|.:|||..  .:.|:|...|...|  .:...|.:...::|:..::.|
plant   152 ALTQAYKDHAQ------DDDSAVNAQLPNSRPMHEITFSTIDRPKLLSQLTSMLGELGLNIQEAH 210

  Fly   135 T--------------------PLEKAKPSLAKRLQDLVEKSGREVKVISFKE------------- 166
            .                    ..|..|.:|.|.::...::...:.|.|:|.|
plant   211 AFSTADGFSLDVFVVDGWSQEETEGLKDALKKEIRKFKDQPCSKQKSITFFEHDKSTNELLPACV 275

  Fly   167 -------QSWQGLKTRSRDATLSRFKGISMGDLDLHTKLSVTPSGETWRGRWQKNDVVAKILAVR 224
                   ..|:                |.|..|.:..|::....||.:||.:...:|..|||...
plant   276 EIPTDGTDEWE----------------IDMKQLKIEKKVACGSYGELFRGTYCSQEVAIKILKPE 324

  Fly   225 QCTPRISRDFNEEFPKLRIFSHPNILPIIGACNSPPNLVTISQFMPRSSLFSLLHGATGVVVDTS 289
            :....:.|:|::|...:|...|.|::..||||...|||..:::||.|.|::..||...| |....
plant   325 RVNAEMLREFSQEVYIMRKVRHKNVVQFIGACTRSPNLCIVTEFMTRGSIYDFLHKHKG-VFKIQ 388

  Fly   290 QAVSFALDVARGMAFLHS---LERIIPTYHL--NSHHVM-IDDDLTARINMGDAKFSFQEKGRIY 348
            ..:..||||::||.:||.   :.|.:.|.:|  :.|.|: :.|...||:.. ::.....|.| .|
plant   389 SLLKVALDVSKGMNYLHQNNIIHRDLKTANLLMDEHEVVKVADFGVARVQT-ESGVMTAETG-TY 451

  Fly   349 QPAWMSPETLQRKQADRNWEACDMWSFAILIWELTTREVPFAEWSPMECGMKIALEGLRVKIPPG 413
            :  ||:||.::.|..|..   .|::|:||::|||.|.|:|::..:|::..:.:..:|||.|||..
plant   452 R--WMAPEVIEHKPYDHR---ADVFSYAIVLWELLTGELPYSYLTPLQAAVGVVQKGLRPKIPKE 511

  Fly   414 TSTHMAKLISICMNEDPGKRPKFDMVVPILEKMRR 448
            |...:.:|:..|..:||..||.|..::.:|.::.|
plant   512 THPKLTELLEKCWQQDPALRPNFAEIIEMLNQLIR 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANK	28..140	CDD:238125	15/89 (17%)
		ANK repeat	33..64	CDD:293786
		Ank_2	38..130	CDD:289560	13/59 (22%)
		ANK repeat	66..97	CDD:293786	5/22 (23%)
		ANK repeat	99..130	CDD:293786	6/34 (18%)
		PK_ILK	196..446	CDD:270959	81/255 (32%)
		STYKc	204..443	CDD:214568	79/244 (32%)
STY17	NP_195303.2	ACT_TyrKc	178..244	CDD:153200	10/65 (15%)
STY17	NP_195303.2	STKc_MAP3K-like	301..541	CDD:270901	79/247 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	126	1.000	Inparanoid score	I1926
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960