DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ilk and AT4G18950

DIOPT Version :9

Sequence 1:	NP_525001.2	Gene:	Ilk / 53573	FlyBaseID:	FBgn0028427	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_567568.1	Gene:	AT4G18950 / 827630	AraportID:	AT4G18950	Length:	459	Species:	Arabidopsis thaliana

Alignment Length:	423	Identity:	103/423 - (24%)
Similarity:	188/423 - (44%)	Gaps:	67/423 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 LHWVAKEGHAKLVETLLQRGSRVNATNMGDDIPLHLAAAHGHRDVVQMLIKERSDVNAVNEHGNT 102
            |.::|.||..:.::.|:..|...|..::.|...||:||..|.:|||::|:..:::|:..:..|:|
plant    47 LMYLANEGDIEGIKELIDSGIDANYRDIDDRTALHVAACQGLKDVVELLLDRKAEVDPKDRWGST 111

  Fly   103 PLHYACFWGYDMICEDLLNAGAQVGIANKDGHTPLEKAKPSLAKRLQDLVEKSGREVKVISFKEQ 167
            |...|.|:....:.:.|...||:..:|..  |....:..|.......:|.....:|:...::...
plant   112 PFADAIFYKNIDVIKILEIHGAKHPMAPM--HVKTAREVPEYEINPSELDFTQSKEITKGTYCMA 174

  Fly   168 SWQGLKTRSRDATLSRFKGISMGDLDLHTKLSVTPSGETWRGRWQKNDVVAKILAVRQCTPRISR 232
            .|:|::             :::..||                    ::|::....||:
plant   175 MWRGIQ-------------VAVKKLD--------------------DEVLSDDDQVRK------- 199

  Fly   233 DFNEEFPKLRIFSHPNILPIIGACNSPPNLVTISQFMPRSSLFSLLHGATGVVVDTSQAVSFALD 297
             |::|...|:...||||:..:||......::.:::::||..|..||.....:...|  ||.:|||
plant   200 -FHDELALLQRLRHPNIVQFLGAVTQSNPMMIVTEYLPRGDLRELLKRKGQLKPAT--AVRYALD 261

  Fly   298 VARGMAFLHSLERIIPTYH--LNSHHVMIDDDLTARI-NMG---------DAKFSFQEKGRIYQP 350
            :||||::||.::. .|..|  |...:::.||....:: :.|         |..|:.|:....|
plant   262 IARGMSYLHEIKG-DPIIHRDLEPSNILRDDSGHLKVADFGVSKLVTVKEDKPFTCQDISCRY-- 323

  Fly   351 AWMSPETLQRKQADRNWEACDMWSFAILIWELTTREVPFAEWSPMECGMKIALEGLRV-KIPPGT 414
              ::||....::.|..   .|::|||:::.|:....:||||....|.....|.:...: |.|...
plant   324 --IAPEVFTSEEYDTK---ADVFSFALIVQEMIEGRMPFAEKEDSEASEAYAGKHRPLFKAPSKN 383

  Fly   415 STHMAK-LISICMNEDPGKRPKFDMVVPILEKM 446
            ..|..| ||..|.:|.|.|||.|..::..||.:
plant   384 YPHGLKTLIEECWHEKPAKRPTFREIIKRLESI 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANK	28..140	CDD:238125	28/101 (28%)
		ANK repeat	33..64	CDD:293786	7/25 (28%)
		Ank_2	38..130	CDD:289560	26/91 (29%)
		ANK repeat	66..97	CDD:293786	11/30 (37%)
		ANK repeat	99..130	CDD:293786	8/30 (27%)
		PK_ILK	196..446	CDD:270959	68/263 (26%)
		STYKc	204..443	CDD:214568	66/252 (26%)
AT4G18950	NP_567568.1	ANK repeat	42..73	CDD:293786	7/25 (28%)
		Ank_2	47..134	CDD:372319	25/86 (29%)
		ANK repeat	75..106	CDD:293786	11/30 (37%)
		ANK repeat	108..133	CDD:293786	6/24 (25%)
		STKc_MAP3K-like	176..413	CDD:270901	70/287 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910