DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ilk and AT2G45910

DIOPT Version :9

Sequence 1:	NP_525001.2	Gene:	Ilk / 53573	FlyBaseID:	FBgn0028427	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_001324111.1	Gene:	AT2G45910 / 819199	AraportID:	AT2G45910	Length:	834	Species:	Arabidopsis thaliana

Alignment Length:	492	Identity:	106/492 - (21%)
Similarity:	180/492 - (36%)	Gaps:	127/492 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GDDHGFS-PLHWVAKEGHAK----LVETLLQRGSRVNATNMGDDIPLHLAAAHGHRDVVQMLIKE 89
            |.|..|: .:.....|.|:.    ..|||.::.:..||.:.       :..|..........:|.
plant   306 GVDDSFNVKIRKATSEAHSSKQEAFAETLRRQKAEKNALDA-------IRRAKQSESAYSEELKR 363

  Fly    90 RSD------------VNAVNEHGNTPLHYACFWGYDMICEDLLNAGAQVG-----IANKDGHTPL 137
            |.|            :...||.             ::|.|:|.:|.||..     ||..||  .:
plant   364 RKDTEIAVAKEKERFITIKNEQ-------------EVIMEELQSAMAQKAMLESQIAKSDG--TM 413

  Fly   138 EKAKPSL---AKRLQDLVE-----KSGREVKVISFKEQSWQGLKTRSRDATL---SRFKGISMGD 191
            ||....|   .|.||.|.:     ::.|:..:...:|     |::.:..:||   ..|...|..:
plant   414 EKLNQKLDIAVKLLQKLRDEREELQTERDRALREAEE-----LRSHAETSTLQLPQYFTDFSFSE 473

  Fly   192 LDLHT-------KLSVTPSGETWRGRWQKNDVVAKILAVRQCTPRISR---DFNEEFPKLRIFSH 246
            ::..|       |:.....|..:.|..:...|..|:|     .|..|:   ::.:|...|....|
plant   474 IEEATNHFDSTLKIGEGGYGSIYVGLLRHTQVAIKML-----NPNSSQGPVEYQQEVDVLSKMRH 533

  Fly   247 PNILPIIGACNSPPNLVTISQFMPRSSLFSLLHGATGVVVDTSQAVSF------ALDVARGMAFL 305
            |||:.:||||  |.....:.:::|..||...|     ...|.|..:|:      |.::...:.||
plant   534 PNIITLIGAC--PEGWSLVYEYLPGGSLEDRL-----TCKDNSPPLSWQNRVRIATEICAALVFL 591

  Fly   306 HSLERIIPTYH--LNSHHVMIDDDLTARIN----------MGDAKFSFQEKGRIYQPAWMSPETL 358
            || .:.....|  |...::::|.:|.::::          .|.........|.:   |::.||
plant   592 HS-NKAHSLVHGDLKPANILLDSNLVSKLSDFGTCSLLHPNGSKSVRTDVTGTV---AYLDPE-- 650

  Fly   359 QRKQADRNWE---ACDMWSFAILIWELTT--------REVPFAEWSPMECG-MKIALEGLRVKIP 411
                |..:.|   ..|::||.|::..|.|        .||.:|    ::.| :...|:.|....|
plant   651 ----ASSSGELTPKSDVYSFGIILLRLLTGRPALRISNEVKYA----LDNGTLNDLLDPLAGDWP 707

  Fly   412 PGTSTHMAKLISICMNEDPGKRPKFDMVV-PILEKMR 447
            ...:..:|:|...|.......||.....| .:||.||
plant   708 FVQAEQLARLALRCCETVSENRPDLGTEVWRVLEPMR 744

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANK	28..140	CDD:238125	27/131 (21%)
		ANK repeat	33..64	CDD:293786	8/35 (23%)
		Ank_2	38..130	CDD:289560	20/112 (18%)
		ANK repeat	66..97	CDD:293786	4/42 (10%)
		ANK repeat	99..130	CDD:293786	7/35 (20%)
		PK_ILK	196..446	CDD:270959	64/290 (22%)
		STYKc	204..443	CDD:214568	60/272 (22%)
AT2G45910	NP_001324111.1	STK_N	46..199	CDD:238947
		Smc	<313..>519	CDD:224117	46/237 (19%)
		STKc_IRAK	487..743	CDD:270968	62/281 (22%)
		Ubox	766..829	CDD:128780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000