DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ilk and AT2G42640

DIOPT Version :9

Sequence 1:	NP_525001.2	Gene:	Ilk / 53573	FlyBaseID:	FBgn0028427	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_181792.4	Gene:	AT2G42640 / 818864	AraportID:	AT2G42640	Length:	781	Species:	Arabidopsis thaliana

Alignment Length:	427	Identity:	104/427 - (24%)
Similarity:	184/427 - (43%)	Gaps:	80/427 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 PLHWVAKEGHAKLVETLLQRGSRVNATNMGDDIPLHLAAAHGHRDVVQM-LIKERSDVNAVNEHG 100
            |..:....|.|: .|:....|..:|..::.:||        ....::|. |:|||. |:..:.:.
plant   389 PADFSGNSGAAE-SESKRTNGRCMNTPDLNNDI--------ARATMMQSDLLKERG-VDDSSPYS 443

  Fly   101 NTPLHYACFWGYDMICEDLLNA------------------GAQVGIANKDGHTPLEKAKPSLAKR 147
            ....:.:   |:.:...||::.                  ..|:.::.:..|:|.|     ::..
plant   444 PDEKNVS---GFQLDSHDLVSGECSTVYPRKSISLPSSPRSYQIQLSERSEHSPQE-----ISHI 500

  Fly   148 LQDLVEKSGREVK-VISFKEQSWQGLKTRSRDATLSRFK-GISMGDLDLHTKLSVTPSGETWRGR 210
            ..:::|....:.| ::.|:|  |        :...|:.| |.|:|.         ..||...||.
plant   501 WNEVLESPMFQNKPLLPFEE--W--------NIDFSKLKVGASVGS---------GTSGVVCRGV 546

  Fly   211 WQKNDVVAKILAVRQCTPRISRDFNEEFPKLRIFSHPNILPIIGACNSPPNLVTISQFMPRSSLF 275
            |.|.:|..||...:|.|....:.|..|...|....|||::.::|||..||.|..::::|...||:
plant   547 WNKTEVAIKIFLGQQLTAENMKVFCNEISILSRLQHPNVILLLGACTKPPQLSLVTEYMSTGSLY 611

  Fly   276 SLLHGATGVVVDTSQAVSFALDVARGMAFLHSL---ERIIPTYH--LNSHHVMIDDDLTARINMG 335
            .::. .....:...:.:....::.||:.::|.:   .|.:.:.:  ||...|.|.|...:|...|
plant   612 DVIR-TRKKELSWQRKLKILAEICRGLMYIHKMGIVHRDLTSANCLLNKSIVKICDFGLSRRMTG 675

  Fly   336 DAKFSFQEKGRIYQPAWMSPETLQRKQADRNWEACDMWSFAILIWELTTREVPFAEWS--PMECG 398
            .|....:..|   .|.||:||.::.:...   |..|::||.:::|||:|...|   |.  |.|..
plant   676 TAVKDTEAAG---TPEWMAPELIRNEPVT---EKSDIFSFGVIMWELSTLSKP---WKGVPKEKV 731

  Fly   399 MKI-ALEGLRVKIPPGTSTHMAKLISICMNEDPGKRP 434
            :.| |.||.|:|||.|.   :.|||:.|.:| |.:||
plant   732 IHIVANEGARLKIPEGP---LQKLIADCWSE-PEQRP 764

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANK	28..140	CDD:238125	21/121 (17%)
		ANK repeat	33..64	CDD:293786	6/26 (23%)
		Ank_2	38..130	CDD:289560	17/110 (15%)
		ANK repeat	66..97	CDD:293786	8/31 (26%)
		ANK repeat	99..130	CDD:293786	4/48 (8%)
		PK_ILK	196..446	CDD:270959	73/247 (30%)
		STYKc	204..443	CDD:214568	72/239 (30%)
AT2G42640	NP_181792.4	EDR1	125..316	CDD:405130
AT2G42640	NP_181792.4	STKc_MAP3K-like	534..773	CDD:270901	74/254 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910